Role of Oral Antioxidant Supplementation in the Current Management of Diabetic Retinopathy


Por: Alfonso-Muñoz EA, Burggraaf-Sánchez de Las Matas R, Mataix Boronat J, Molina Martín JC and Desco C

Publicada: 1 abr 2021 Ahead of Print: 13 abr 2021
Resumen:
Oxidative stress has been postulated as an underlying pathophysiologic mechanism of diabetic retinopathy (DR), the main cause of avoidable blindness in working-aged people. This review addressed the current daily clinical practice of DR and the role of antioxidants in this practice. A systematic review of the studies on antioxidant supplementation in DR patients was presented. Fifteen studies accomplished the inclusion criteria. The analysis of these studies concluded that antioxidant supplementation has a IIB level of recommendation in adult Type 1 and Type 2 diabetes mellitus subjects without retinopathy or mild-to-moderate nonproliferative DR without diabetic macular oedema as a complementary therapy together with standard medical care.

Filiaciones:
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 FISABIO-Oftalmología Médica (FOM), Vitreoretinal Unit, 46015 Valencia, Spain

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 Servicio de Oftalmología, Hospital General Universitario de Castellón, 12004 Castellón, Spain

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 FISABIO-Oftalmología Médica (FOM), Vitreoretinal Unit, 46015 Valencia, Spain

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 Servicio de Oftalmología, Hospital Universitario San Juan, 03550 Alicante, Spain

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 FISABIO-Oftalmología Médica (FOM), Vitreoretinal Unit, 46015 Valencia, Spain
ISSN: 16616596





INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Editorial
MDPI AG, Switzerland, Suiza
Tipo de documento: Review
Volumen: 22 Número: 8
Páginas:
WOS Id: 000644362100001
ID de PubMed: 33924714
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