Evaluation of Intraocular Pressure and Other Biomechanical Parameters to Distinguish between Subclinical Keratoconus and Healthy Corneas


Por: Peris-Martínez C, Díez-Ajenjo MA, García-Domene MC, Pinazo-Durán MD, Luque-Cobija MJ, Del Buey-Sayas MÁ and Ortí-Navarro S

Publicada: 1 may 2021 Ahead of Print: 28 abr 2021
Categoría: Medicine (miscellaneous)

Resumen:
(1) Purpose: To assess the main corneal response differences between normal and subclinical keratoconus (SCKC) with a Corvis(R) ST device. (2) Material and Methods: We selected 183 eyes of normal patients, of a mean age of 33 +/- 9 years and 16 eyes of patients with SCKC of a similar mean age. We measured best corrected visual acuity (BCVA) and corneal topography with a Pentacam HD device to select the SCKC group. Biomechanical measurements were performed using the Corvis(R) ST device. We carried out a non-parametric analysis of the data with SPSS software (Wilcoxon signed rank-test). (3) Results: We found statistically significant differences between the control and SCKC groups in some corneal biomechanical parameters: first and second applanation time (p = 0.05 and p = 0.02), maximum deformation amplitude (p = 0.016), highest concavity radius (p = 0.007), and second applanation length and corneal velocity ((p = 0.039 and p = 0.016). (4) Conclusions: Our results show that the use of normalised biomechanical parameters provided by noncontact tonometry, combined with a discriminant function theory, is a useful tool for detecting subclinical keratoconus.

Filiaciones:
:
 FISABIO Oftalmología Médica (FOM), Anterior Segment and Cornea and External Eye Diseases Unit, Bifurcación Pío Baroja-General Avilés, 12, E-46015 Valencia, Spain

 Surgery Department, Ophthalmology, School of Medicine, University of Valencia, Av. Blasco Ibáñez, 15, E-46010 Valencia, Spain

 Aviño Peris Eye Clinic, Avinguda de l'Oest, 34, E-46001 Valencia, Spain

:
 FISABIO Oftalmología Médica (FOM), Anterior Segment and Cornea and External Eye Diseases Unit, Bifurcación Pío Baroja-General Avilés, 12, E-46015 Valencia, Spain

 Optics, Optometry and Vision Sciences Department, School of Physics, University of Valencia, Dr. Moliner, 50, E-46100 Valencia, Spain

:
 FISABIO Oftalmología Médica (FOM), Anterior Segment and Cornea and External Eye Diseases Unit, Bifurcación Pío Baroja-General Avilés, 12, E-46015 Valencia, Spain

 Optics, Optometry and Vision Sciences Department, School of Physics, University of Valencia, Dr. Moliner, 50, E-46100 Valencia, Spain

:
 Surgery Department, Ophthalmology, School of Medicine, University of Valencia, Av. Blasco Ibáñez, 15, E-46010 Valencia, Spain

:
 FISABIO Oftalmología Médica (FOM), Anterior Segment and Cornea and External Eye Diseases Unit, Bifurcación Pío Baroja-General Avilés, 12, E-46015 Valencia, Spain

 Optics, Optometry and Vision Sciences Department, School of Physics, University of Valencia, Dr. Moliner, 50, E-46100 Valencia, Spain

Del Buey-Sayas MÁ:
 Hospital Lozano Blesa, Anterior Segment and Cornea and External Eye Diseases, E-46015 Zaragoza, Spain

Ortí-Navarro S:
 Optics, Optometry and Vision Sciences Department, School of Physics, University of Valencia, Dr. Moliner, 50, E-46100 Valencia, Spain
ISSN: 20770383





Journal of Clinical Medicine
Editorial
MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, Suiza
Tipo de documento: Article
Volumen: 10 Número: 9
Páginas:
WOS Id: 000650354000001
ID de PubMed: 33924937
imagen Green Published, gold

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