ENT involvement in Leishmania infections
Por:
Callejo, F, Garcia, R, Azpilicueta, M and Aguayo, J
Publicada:
1 ene 2021
Ahead of Print:
1 ene 2021
Categoría:
Otorhinolaryngology
Resumen:
Introduction: Leishmaniasis comprises a group of diseases caused by protozoan parasites of the genus Leishmania that are transmitted by the bite of infected phlebotomine mosquitoes from animal reservoirs. Three different clinical forms are generated: cutaneous, mucocutaneous and visceral. We present the findings in the head and neck of this disease observed in our health area.
Patients and methods: A review of the last 26 years in our hospital, noting the clinical, diagnostic and therapeutic characteristics of the cases detected.
Results: Thirteen cases were identified, 7 cutaneous, 4 mucocutaneous and 2 visceral or kalaazar. The mean age was 53.7 +/- 10.8 years. Immunodeficiency was identified in 61% of the cases. The incidence of the disease was 1.5:100,000 inhabitants/year, with a prevalence of 2%. Of those infected, 69% had involvement of the ear-nose-throat area. In 12 cases the diagnosis was established by biopsy of the lesions. The time from clinical debut to diagnosis ranged from 3 to 10 months. Antimony compounds were used as treatment in 11 patients and amphotericin B in 3, alone or combined with the former. One cutaneous form resolved with excision of the lesion. Ninety-two percent healed clinically and parasitologically.
Conclusions: Leishmaniasis in Spain frequently entails cutaneous and mucocutaneous involvement, often of the skin of the head, face and neck or upper-airway mucosa. Its clinical presentation varies greatly, and it should be suspected if there is no response to conventional therapies and in conditions of immunodeficiency. (C) 2020 Sociedad Espanola de Otorrinolaringologia y Cirugia de Cabeza y CueBo. Published by Elsevier Espana, S.L.U. All rights reserved.
Filiaciones:
:
Hosp Requena, Serv Otorrinolaringol, Valencia, Spain
:
Hosp Requena, Serv Otorrinolaringol, Valencia, Spain
:
Hosp Requena, Serv Otorrinolaringol, Valencia, Spain
:
Hosp Requena, Serv Otorrinolaringol, Valencia, Spain
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