A Cross-Sectional Study of Seroprevalence of Strongyloidiasis in Pregnant Women (Peruvian Amazon Basin)
Por:
Ortiz-Martinez, S, Ramos-Rincon, J, Vasquez-Chasnamote, M, Alarcon-Baldeon, J, Parraguez-de-la-Cruz, J, Gamboa-Paredes, O, Schillyk-Guerra, P, Espinoza-Venegas, L, Pinedo-Cancino, V, Perez-Tanoira, R, Gorgolas-Hernandez-Mora, M, Casapia-Morales, M, Ramos-Rincon, M, Gimeno, A, Llenas-Garcia, J, Gorgolas-Hernandez-Mora, M, Perez-Tanoira, R, Prieto, L, Ortiz-Martinez, S, Vasquez-Chasnamote, M, Gamboa-Paredes, O, Alarcon-Baldeon, J, Schillyk-Guerra, P, Bardales-Vasquez, J, Perez-Bardales, G, Silva, A, Pezo-Flores, R, Espinoza-Venegas, L, Cancino, V, Morales, M and Spanish-Peruvian Chagas HTLV Stron
Publicada:
1 may 2020
Resumen:
Strongyloidiasis is a soil-transmitted helminthiasis with a high global prevalence. Objectives: We aimed to evaluate the prevalence of Strongyloides stercoralis infection and assess strongyloidiasis serology as a screening technique in the Peruvian Amazon. Material and Methods: We performed a cross-sectional study of strongyloidiasis in 300 pregnant women in Iquitos (Peru) from 1 May 2019 to 15 June 2019. Women were tested using serology (Strongyloides IgG IVD-ELISA kit) as an index test and the modified Baermann technique and/or charcoal fecal culture as the parasitological reference standard. Results: The reference tests showed S. stercoralis in the stool of 30 women (prevalence: 10%; 95% confidence interval [CI] 7.1% to 13.9%), while 101 women tested positive on the blood test (prevalence: 33.7%; 95% CI 28.6% to 39.4%). Fourteen of the 15 women (93.3%) with positive results according to the modified Baermann technique, and 14 of the 23 women (56.5%) with positive charcoal cultures also had positive serological results. Serology showed a sensitivity of 63.3% and a negative predictive value of 94.4%. Conclusion: In Iquitos, pregnant women have a high prevalence of S stercoralis. S. stercoralis ELISA could be an excellent tool for population-based screening, as it has a high negative predictive value that can help to rule out the presence of active infection.
Filiaciones:
Ortiz-Martinez, S:
Serv Salud Castellano Manchego, Consultorio El Ballestero, Albacete 2614, Spain
Consultorio El Ballestero, Albacete, Spain
Ramos-Rincon, J:
Univ Miguel Hernandez Elche, Dept Med Clin, Alicante 03550, Spain
Hosp Gen Univ Alicante, Serv Med Interna, Alicante 03010, Spain
Vasquez-Chasnamote, M:
Univ Nacl Amazonia Peruana, Ctr Invest Recursos Nat, Iquitos 16001, Peru
Alarcon-Baldeon, J:
Assoc Civil Selva Amazon, Lab Clin, Iquitos 16001, Peru
Parraguez-de-la-Cruz, J:
Assoc Civil Selva Amazon, Lab Clin, Iquitos 16001, Peru
Gamboa-Paredes, O:
Assoc Civil Selva Amazon, Asistente Invest, Iquitos 16001, Peru
Schillyk-Guerra, P:
Assoc Civil Selva Amazon, Lab Clin, Iquitos 16001, Peru
Assoc Civil Selva Amazon, Iquitos, Peru
Espinoza-Venegas, L:
Hosp Reg Loreto, Serv Enfermedades Infecciosas & Med Trop, Iquitos 16001, Peru
Pinedo-Cancino, V:
Univ Nacl Amazonia Peruana, Lab Biol Mol & Inmunol, Unidad Especializada LIPNAA CIRNA, Iquitos 16001, Peru
Perez-Tanoira, R:
Hosp Univ Principe Asturias, Serv Microbiol, Alcala De Henares 28802, Spain
Hosp Univ Fdn Jimenez Diaz, Madrid, Spain
Univ Autonoma Madrid, Madrid, Spain
Gorgolas-Hernandez-Mora, M:
Hosp Univ Fdn Jimenez Diaz, Div Enfermedades Infecciosas, Madrid 28040, Spain
Univ Autonoma Madrid, Dept Med, Madrid 28029, Spain
Hosp Univ Fdn Jimenez Diaz, Madrid, Spain
Univ Autonoma Madrid, Madrid, Spain
Casapia-Morales, M:
Hosp Reg Loreto, Serv Enfermedades Infecciosas & Med Trop, Iquitos 16001, Peru
Assoc Civ Selva Amazon, Dept Med, Iquitos 16001, Peru
Univ Nacl Amazonia Peruana, Fac Med, Iquitos 496, Peru
Ramos-Rincon, M:
Hosp Gen Univ Alicante, Alicante, Spain
Univ Miguel Hernandez, Alicante, Spain
Gimeno, A:
Hosp Gen Univ Alicante, Alicante, Spain
Univ Miguel Hernandez, Alicante, Spain
:
Hosp Vega Baja, Orihuela, Spain
Gorgolas-Hernandez-Mora, M:
Hosp Univ Fdn Jimenez Diaz, Div Enfermedades Infecciosas, Madrid 28040, Spain
Univ Autonoma Madrid, Dept Med, Madrid 28029, Spain
Hosp Univ Fdn Jimenez Diaz, Madrid, Spain
Univ Autonoma Madrid, Madrid, Spain
Perez-Tanoira, R:
Hosp Univ Principe Asturias, Serv Microbiol, Alcala De Henares 28802, Spain
Hosp Univ Fdn Jimenez Diaz, Madrid, Spain
Univ Autonoma Madrid, Madrid, Spain
Prieto, L:
Hosp Univ Fdn Jimenez Diaz, Madrid, Spain
Univ Autonoma Madrid, Madrid, Spain
Ortiz-Martinez, S:
Serv Salud Castellano Manchego, Consultorio El Ballestero, Albacete 2614, Spain
Consultorio El Ballestero, Albacete, Spain
Vasquez-Chasnamote, M:
Univ Nacl Amazonia Peruana, Ctr Invest Recursos Nat, Iquitos 16001, Peru
Gamboa-Paredes, O:
Assoc Civil Selva Amazon, Iquitos, Peru
Alarcon-Baldeon, J:
Assoc Civil Selva Amazon, Iquitos, Peru
Schillyk-Guerra, P:
Assoc Civil Selva Amazon, Lab Clin, Iquitos 16001, Peru
Assoc Civil Selva Amazon, Iquitos, Peru
Bardales-Vasquez, J:
Assoc Civil Selva Amazon, Iquitos, Peru
Perez-Bardales, G:
Assoc Civil Selva Amazon, Iquitos, Peru
Silva, A:
Assoc Civil Selva Amazon, Iquitos, Peru
Pezo-Flores, R:
Assoc Civil Selva Amazon, Iquitos, Peru
Espinoza-Venegas, L:
Hosp Reg Loreto, Iquitos, Peru
Cancino, V:
Assoc Civil Selva Amazon, Iquitos, Peru
Univ Nacl Amazonia Peruana, Lab Biol Mol & Inmunol, Unidad Especializada, Iquitos, Peru
Morales, M:
Univ Nacl Amazonia Peruana, Hosp Reg Loreto, Iquitos, Peru
Univ Nacl Amazonia Peruana, Assoc Civil Selva Amazon, Iquitos, Peru
gold, Green Published
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