The prevalence of rheumatoid arthritis in Spain
Por:
Silva-Fernández L, Macía-Villa C, Seoane-Mato D, Cortés-Verdú R, Romero-Pérez A, Quevedo-Vila V, Fábregas-Canales D, Antón-Pagés F, Añez G, Brandy A, Martínez-Dubois C, Rubio-Muñoz P, Sánchez-Piedra C, Díaz-González F and Bustabad-Reyes S
Publicada:
9 dic 2020
Ahead of Print:
9 dic 2020
Categoría:
Multidisciplinary
Resumen:
Rheumatoid arthritis (RA) prevalence is believed to be around 1% worldwide, although it varies considerably among different populations. The aim of EPISER2016 study was to estimate the prevalence of RA in the general adult population in Spain. We designed a population-based cross-sectional study. A national survey was conducted between November 2016 and October 2017 involving a probabilistic sample from the general population aged 20 years or older. Subjects were randomly selected for phone screening using a computer-assisted telephone interviewer system. Positive RA screening results were evaluated by a rheumatologist. Cases fulfilled the 1987 ACR and/or the 2010 ACR/EULAR criteria; previous diagnosis established by a rheumatologist and clearly identified in medical records were also accepted regardless of the criteria used. Prevalence estimates with 95% CI were calculated taking into account the design of the sample (weighting based on age, sex, and geographic origin using as a reference the distribution of the population in Spain). 4916 subjects participated in the study and 39 RA cases were confirmed. RA estimated prevalence was 0.82% (95% CI 0.59-1.15). Mean age of RA cases was 60.48 (14.85) years, they were more frequently women (61.5%), from urban areas (74.4%), non-smokers (43.6%), and with a high body mass index (53.8% with overweight). Extrapolating to the population in Spain (approximately 37 million are >= 20 years old), it was estimated that there were between 220,000 and 430,000 people aged 20 years or older with RA. No undiagnosed cases were detected, which could be related to the establishment of early arthritis clinics around the country, increasing the rates of diagnosis during early phases of RA.
Filiaciones:
Silva-Fernández L:
Rheumatology Department, Complexo Hospitalario Universitario de A Coruña, As Xubias 84, 15006, A Coruña, Spain.
Macía-Villa C:
Rheumatology, Hospital Universitario Severo Ochoa, Madrid, Spain
Seoane-Mato D:
Research Unit, Spanish Society of Rheumatology, Madrid, Spain
:
Rheumatology, Hospital General de Ontinyent, Ontinyent, Valencia, Spain
Romero-Pérez A:
Rheumatology, Complejo Hospitalario de Jaén, Jaén, Spain
Quevedo-Vila V:
Rheumatology, Hospital Comarcal Monforte de Lemos, Monforte de Lemos, Lugo, Spain
Fábregas-Canales D:
Rheumatology, Hospital de Barbastro, Barbastro, Huesca, Spain
Antón-Pagés F:
Rheumatology, Complejo Asistencial Universitario de Palencia, Palencia, Spain
Añez G:
Rheumatology, Hospital Universitario Puerta del Mar, Cádiz, Spain
Brandy A:
Rheumatology, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain
Martínez-Dubois C:
Rheumatology, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain
Rubio-Muñoz P:
Rheumatology, Hospital Universitari Germans Trias I Pujol, Badalona, Barcelona, Spain
Sánchez-Piedra C:
Research Unit, Spanish Society of Rheumatology, Madrid, Spain
Díaz-González F:
Universidad de La Laguna, La Laguna, Santa Cruz de Tenerife, Spain
Rheumatology, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain
Bustabad-Reyes S:
Rheumatology, Hospital Universitario de Canarias, La Laguna, Santa Cruz de Tenerife, Spain
Green Published, gold
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