Safety, activity, and molecular heterogeneity following neoadjuvant non-pegylated liposomal doxorubicin, paclitaxel, trastuzumab, and pertuzumab in HER2-positive breast cancer (Opti-HER HEART): an open-label, single-group, multicenter, phase 2 trial.

Por: Gavila, J, Oliveira, M, Pascual, T, Perez-Garcia, J, Gonzalez, X, Canes, J, Pare, L, Calvo, I, Ciruelos, E, Munoz, M, Virizuela, J, Ruiz, I, Andres, R, Perello, A, Martinez, J, Morales, S, Marin-Aguilera, M, Martinez, D, Quero, J, Llombart-Cussac, A and Prat, A

---

Publicada: 9 ene 2019 Ahead of Print: 9 ene 2019

---

---

Filiaciones:
Gavila, J:
 Fdn Inst Valenciano Oncol, Valencia, Spain

Oliveira, M:
 Vall dHebron Univ Hosp, Vall dHebron Inst Oncol, Barcelona, Spain

Pascual, T:
 August Pi & Sunyer Biomed Res Inst IDIBAPS, Barcelona, Spain

 Hosp Clin Barcelona, Barcelona, Spain

 SOLTI Breast Canc Res Grp, Barcelona, Spain

Perez-Garcia, J:
 Vall dHebron Univ Hosp, Vall dHebron Inst Oncol, Barcelona, Spain

 Hosp Quiron, Inst Oncol Baselga, Barcelona, Spain

Gonzalez, X:
 SOLTI Breast Canc Res Grp, Barcelona, Spain

 Hosp Gen Cataluna, Inst Oncol Rosell, Barcelona, Spain

Canes, J:
 SOLTI Breast Canc Res Grp, Barcelona, Spain

Pare, L:
 August Pi & Sunyer Biomed Res Inst IDIBAPS, Barcelona, Spain

Calvo, I:
 Ctr Integral Oncol Clara Campal, Madrid, Spain

Ciruelos, E:
 Hosp 12 Octubre, Madrid, Spain

Munoz, M:
 August Pi & Sunyer Biomed Res Inst IDIBAPS, Barcelona, Spain

 Hosp Clin Barcelona, Barcelona, Spain

Virizuela, J:
 Hosp Univ Virgen Macarena, Seville, Spain

Ruiz, I:
 Hosp Univ St Joan Reus, Reus, Spain

Andres, R:
 Hosp Clin Univ Lozano Blesa, Zaragoza, Spain

Perello, A:
 Hosp Univ Son Espases, Palma De Mallorca, Spain

Martinez, J:
 Hosp Univ Virgen Arrixaca, Murcia, Spain

Morales, S:
 Hosp Arnau Vilanova, Lleida, Spain

Marin-Aguilera, M:
 August Pi & Sunyer Biomed Res Inst IDIBAPS, Barcelona, Spain

Martinez, D:
 August Pi & Sunyer Biomed Res Inst IDIBAPS, Barcelona, Spain

Quero, J:
 Hosp Sagrado Corazon, Barcelona, Spain

:
 Hosp Arnau Vilanova, Valencia, Spain

Prat, A:
 August Pi & Sunyer Biomed Res Inst IDIBAPS, Barcelona, Spain

 Hosp Clin Barcelona, Barcelona, Spain

 SOLTI Breast Canc Res Grp, Barcelona, Spain