Association between non-adherence behaviors, patients? experience with healthcare and beliefs in medications: a survey of patients with different chronic conditions


Por: Cea-Calvo L, Marín-Jiménez I, de Toro J, Fuster-RuizdeApodaca MJ, Fernández G, Sánchez-Vega N and Orozco D

Publicada: 1 feb 2020 Ahead of Print: 1 oct 2019
Categoría: Medicine (miscellaneous)

Resumen:
Objective: The objective of the current work was to assess the frequency of non-adherence behaviors and potential association with patients? experience with healthcare and beliefs in medicines self-reported by patients with four different chronic conditions. Methods: Patients responded anonymously to a survey comprising five non-adherence behaviors (based on physician and patient input), an assessment of patients? experience with healthcare using the validated Instrument to Evaluate the EXperience of PAtients with Chronic diseases (IEXPAC), and a validated Spanish version of the Beliefs about Medicines Questionnaire (BMQ). Associations of non-adherence behavior were analyzed using logistic regression models. Results: Of 1530 respondents, 53.1% reported ?1 non-adherence behavior. Non-adherence rates were 59.8% in diabetes mellitus (DM), 56.0% in rheumatic disease, 55.6% in inflammatory bowel disease, and 42.8% in human immunodeficiency virus (HIV) infection patients (p < .001). IEXPAC and BMQ scores were higher in adherent vs. non-adherent patients. In multivariate analysis, non-adherence behavior was strongly associated with lower overall BMQ, lower BMQ Necessity scores and higher BMQ Concerns scores (p < .001 for all), and with a lower IEXPAC self-management score (p = .007), but not with the overall IEXPAC score. Non-adherence was more frequent in DM patients compared with HIV infection patients (p < .001). Conclusions: Patients? beliefs in medicines-a lower perception for the necessity of medication, and higher concerns in taking medication-and low patient self-management experience score were associated with non-adherence behavior. These are modifiable aspects that need to be addressed to increase medication adherence in chronic disease.

Filiaciones:
Cea-Calvo L:
 Medical Affairs Department, Merck Sharp & Dohme Spain, Madrid, Spain

Marín-Jiménez I:
 IBD Unit, Gastroenterology Department, Clinical Research Institute Gregorio Marañón (IiSGM), Gregorio Marañón University Hospital, Madrid, Spain

de Toro J:
 Rheumatology Department, A Coruña University Hospital, A Coruña, Spain

Fuster-RuizdeApodaca MJ:
 SEISIDA (Spanish AIDS Multidisciplinary Society), Madrid, Spain

Fernández G:
 Medical Affairs Department, Merck Sharp & Dohme Spain, Madrid, Spain

Sánchez-Vega N:
 Medical Affairs Department, Merck Sharp & Dohme Spain, Madrid, Spain

Orozco D:
 Clinical Medicine Department, Miguel Hernandez University, San Juan de Alicante, Spain
ISSN: 03007995





CURRENT MEDICAL RESEARCH AND OPINION
Editorial
TAYLOR & FRANCIS LTD, 2-4 PARK SQUARE, MILTON PARK, ABINGDON OR14 4RN, OXON, ENGLAND, Reino Unido
Tipo de documento: Article
Volumen: 36 Número: 2
Páginas: 293-300
WOS Id: 000490457700001
ID de PubMed: 31580168
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