Non-coding RNAs and Coronary Artery Disease.
Por:
Cardona-Monzonís A, García-Giménez JL, Mena-Mollá S, Pareja-Galeano H, de la Guía-Galipienso F, Lippi G, Pallardó FV and Sanchis-Gomar F
Publicada:
1 ene 2020
Resumen:
Coronary artery disease (CAD) is the leading death cause worldwide. Non-coding RNA (ncRNA) are key regulators of genetic expression and thus can affect directly or indirectly the development and progression of different diseases. ncRNA can be classified in several types depending on the length or structure, as long non-coding RNA (lncRNA), microRNA (miRNA) and circularRNA (circRNA), among others. These types of RNA are present within cells or in circulation, and for this reason they have been used as biomarkers of different diseases, therefore revolutionizing precision medicine. Recent research studied the capability of circulating ncRNA to inform about CAD presence and predict the outcome of the disease. In this chapter we present a list of the miRNA, lncRNA and circRNA which are potential biomarkers of CAD.
Filiaciones:
Cardona-Monzonís A:
Center for Biomedical Network Research-Instituto de Salud Carlos III. Department of Physiology, School of Medicine, University of Valencia and INCLIVA Biomedical Research Institute, Valencia, Spain
García-Giménez JL:
Center for Biomedical Network Research-Instituto de Salud Carlos III. Department of Physiology, School of Medicine, University of Valencia and INCLIVA Biomedical Research Institute, Valencia, Spain
Mena-Mollá S:
Department of Physiology, School of Medicine, University of Valencia, Valencia, Spain
Pareja-Galeano H:
Universidad Europea de Madrid, Madrid, Spain
:
Department of Cardiology, Hospital de la Marina Baixa, Alicante, Spain
Lippi G:
Section of Clinical Biochemistry, University of Verona, Verona, Italy
Pallardó FV:
Center for Biomedical Network Research-Instituto de Salud Carlos III. Department of Physiology, School of Medicine, University of Valencia and INCLIVA Biomedical Research Institute, Valencia, Spain
Sanchis-Gomar F:
Department of Physiology, Faculty of Medicine, University of Valencia and INCLIVA Biomedical Research Institute, Valencia, Spain.
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