Clinicoepidemiological characteristics of viral hepatitis in migrants and travellers of the plus Redivi network
Por:
Henriquez-Camacho C, Serre N, Norman F, Sánchez-Montalvá A, Torrus D, Goikoetxea AJ, Herrero-Martínez JM, Ruiz-Giardín JM, Treviño B, Monge-Maillo B, Molina I, Rodríguez A, García M, López-Vélez R and Pérez-Molina JA
Publicada:
1 may 2019
Ahead of Print:
6 feb 2019
Resumen:
Background: Continuous growth of mobile populations has influenced the global epidemiology of infectious diseases, including chronic and acute viral hepatitis.
Method: A prospective observational multicentre study was performed in a Spanish network of imported infections. Viral hepatitis cases from January 2009 to September 2017 were included.
Results: Of 14,546 records, 723 (4.97%) had imported viral hepatitis, including 48 (6.64%) acute cases and 675 (93.36%) chronic cases. Of the 48 acute cases, 31 were travellers and immigrants returning from visiting friends or relatives (VFR), while 19 (61%) were acute Hepatitis A or Hepatitis B. Only 18.2% of VFR immigrants and 35% of travellers received pre-travel advice. Acute hepatitis was more frequent in VFR immigrants (AOR 2.59, CI95% 1.20-5.60) and travellers (AOR 2.83, CI95% 1.46-5.50) than immigrants. Of the 675 Chronic cases, 570 were immigrants, and 439 (77%) had chronic Hepatitis B. Chronic hepatitis was more frequent in immigrants (AOR 20.22, CI95% 11.64-35.13) and VFR immigrants (AOR 11.12, CI95% 6.20-19.94) than travellers.
Conclusions: Chronic viral hepatitis was typical of immigrants, acute viral hepatitis was common among travellers, and VFR immigrants had mixed risk. Improving pre-travel consultation and screening of immigrants may contribute to preventing new cases of viral hepatitis and avoiding community transmission.
Filiaciones:
Henriquez-Camacho C:
National Referral Unit for Tropical Diseases, Infectious Diseases Department, Ramón y Cajal University Hospital, IRYCIS, Carretera de Colmenar Km 9, 1, 28034, Madrid, Spain
Serre N:
Unitat Medicina Tropical I Salut Internacional Vall d´Hebron-Drassanes, PROSICS, Av de Drassanes 17-21, 08001, Barcelona, Spain
Norman F:
National Referral Unit for Tropical Diseases, Infectious Diseases Department, Ramón y Cajal University Hospital, IRYCIS, Carretera de Colmenar Km 9, 1, 28034, Madrid, Spain
Sánchez-Montalvá A:
Department of Infectious Diseases, Vall d´Hebron University Hospital, Universitat Autonoma de Barcelona, PROSICS Barcelona, Passeig Vall d´Hebron 119-129, 08035, Barcelona, Spain
Torrus D:
Alicante University Hospital, Calle Pintor Baeza 11, 03010, Alicante, Spain
Goikoetxea AJ:
Hospital Universitario de Cruces, Plaza de las Cruces s/n, 48903, Bizkaia, Spain
Herrero-Martínez JM:
Hospital Universitario Doce de Octubre, Av. Cordoba, s/n, 28041, Madrid, Spain
Ruiz-Giardín JM:
Hospital Universitario de Fuenlabrada, Camino del Molino, 2, 28942, Madrid, Spain
Treviño B:
Unitat Medicina Tropical I Salut Internacional Vall d´Hebron-Drassanes, PROSICS, Av de Drassanes 17-21, 08001, Barcelona, Spain
Monge-Maillo B:
National Referral Unit for Tropical Diseases, Infectious Diseases Department, Ramón y Cajal University Hospital, IRYCIS, Carretera de Colmenar Km 9, 1, 28034, Madrid, Spain
Molina I:
Department of Infectious Diseases, Vall d´Hebron University Hospital, Universitat Autonoma de Barcelona, PROSICS Barcelona, Passeig Vall d´Hebron 119-129, 08035, Barcelona, Spain
Rodríguez A:
Hospital Universitario Central de Asturias, Av. Roma, s/n, 33011, Oviedo Principado de Asturias, Spain
García M:
Consorcio Hospital General Universitario de Valencia, Avenida Tres Cruces, 2, 46014, Valencia, Spain
López-Vélez R:
National Referral Unit for Tropical Diseases, Infectious Diseases Department, Ramón y Cajal University Hospital, IRYCIS, Carretera de Colmenar Km 9, 1, 28034, Madrid, Spain
Pérez-Molina JA:
National Referral Unit for Tropical Diseases, Infectious Diseases Department, Ramón y Cajal University Hospital, IRYCIS, Carretera de Colmenar Km 9, 1, 28034, Madrid, Spain
Aguilera P:
Centro de Atención Primaria Guayaba, Comunidad de Madrid, Spain
Serrano MM:
Complejo Hospitalario Universitario de Albacete, Comunidad de Castilla-La Mancha, Spain
Rodriguez MG:
Consorcio Hospital General Universitario de Valencia, Comunidad Valenciana, Spain
Menendez MD:
Hospital Carlos III-La Paz, Comunidad de Madrid, Spain
Meije Y:
Hospital de Barcelona, Cataluña, Spain
Martínez-Montauti J:
Hospital de Barcelona, Cataluña, Spain
Sanz X:
Hospital de Barcelona, Cataluña, Spain
:
Hospital de la Vega Baja de Orihuela, Comunidad Valenciana, Spain
:
Hospital de la Vega Baja de Orihuela, Comunidad Valenciana, Spain
:
Hospital de la Vega Baja de Orihuela, Comunidad Valenciana, Spain
:
Hospital de la Vega Baja de Orihuela, Comunidad Valenciana, Spain
:
Hospital General de Elche, Comunidad Valenciana, Spain
:
Hospital General de Elche, Comunidad Valenciana, Spain
Romero M:
Hospital General de Elda-Virgen de la Salud, Comunidad Valenciana, Spain
:
Hospital General de Elda-Virgen de la Salud, Comunidad Valenciana, Spain
Torrus D:
Hospital General Universitario de Alicante, Comunidad Valenciana, Spain
Ramos J:
Hospital General Universitario de Alicante, Comunidad Valenciana, Spain
Malmierca E:
Hospital Infanta Sofía, Comunidad de Madrid, Spain
Perez-Ayala A:
Hospital Universitario 12 de Octubre, Madrid Comunidad de Madrid, Spain
Herrero JM:
Hospital Universitario 12 de Octubre, Madrid Comunidad de Madrid, Spain
Lizasoain M:
Hospital Universitario 12 de Octubre, Madrid Comunidad de Madrid, Spain
Rojo P:
Hospital Universitario 12 de Octubre, Madrid Comunidad de Madrid, Spain
Matarranz M:
Hospital Universitario 12 de Octubre, Madrid Comunidad de Madrid, Spain
Zarco C:
Hospital Universitario 12 de Octubre, Madrid Comunidad de Madrid, Spain
Rodriguez-Guardado A:
Hospital Universitario Central de Asturias, Oviedo Principado de Asturias, Spain
Suárez JF:
Hospital Universitario Central de Asturias, Oviedo Principado de Asturias, Spain
Boga Ribeiro JA:
Hospital Universitario Central de Asturias, Oviedo Principado de Asturias, Spain
Aguirre JG:
Hospital Universitario Cruces de Barakaldo, Bilbao, España País Vasco, Spain
Zubero Sulibarría MZ:
Hospital Universitario de Basurto de Bilbao, País Vasco, Spain
Ruiz Giardin JM:
Hospital Universitario de Fuenlabrada, Comunidad de Madrid, Spain
Sanmartín López JV:
Hospital Universitario de Fuenlabrada, Comunidad de Madrid, Spain
Arribas MV:
Hospital Universitario Fundación de Alcorcón, Comunidad de Madrid, Spain
Muñoz EC:
Hospital Universitario La Fe de Valencia, Comunidad Valenciana, Spain
Ribas AM:
Hospital Universitario Son Espases, Islas Baleares, Spain
Vera MP:
Hospital Universitario Son Espases, Islas Baleares, Spain
Molina I:
Hospital Universitario Vall d'Hebron, Cataluña, Spain
Montalvá AS:
Hospital Universitario Vall d'Hebron, Cataluña, Spain
Salvador F:
Hospital Universitario Vall d'Hebron, Cataluña, Spain
Dominguez Á:
Hospital Universitario Virgen de la Macarena de Sevilla, Andalucía, Spain
Norman F:
Servicio de Enfermedades Infecciosas, Hospital Ramón y Cajal, Comunidad de Madrid, Spain
Treviño-Maruri B:
Unitat de Salut Internacional Drassanes, PROSICS, Cataluña, Spain
Delcor NS:
Unitat de Salut Internacional Drassanes, PROSICS, Cataluña, Spain
Soriano-Arandes A:
Unitat de Salut Internacional Drassanes, PROSICS, Cataluña, Spain
Ciruelo DP:
Unitat de Salut Internacional Drassanes, PROSICS, Cataluña, Spain
Bocanegra C:
Unitat de Salut Internacional Drassanes, PROSICS, Cataluña, Spain
|