Health-related quality of life in individuals with metabolic syndrome: A cross-sectional study
Por:
Marcos-Delgado A, López-García E, Martínez-González MA, Salas-Salvadó J, Corella D, Fitó M, Romaguera D, Vioque J, Alonso-Gómez AM, Wärnberg J, Martínez JA, Serra-Majem L, Estruch R, Fernández-García JC, Lapetra J, Pintó X, Tur JA, López-Miranda J, Cano-Ibañez N, Delgado-Rodríguez M, Matía-Martín P, Daimiel L, Carriedo E, Vidal J, Vázquez C, Ros E, Lozano-Oloriz E, Bulló M, Sorlí JV, Zomeño MD, Fiol M, González-Palacios S, Sorto-Sánchez C, Pérez-Farinós N, Goñi-Ruiz N, Sanchez-Villegas A, Muñoz-Garach A, Santos-Lozano JM, Galera A, Bouzas C, Toledo E, Babio N, González JI, Del Val-García JL, Moñino M, Martínez-Vergaran MC, Goicolea-Güemez L, Galilea-Zabalza I, Basora J, Muñoz MA, Builf P, Fernández-Villa T and PREDIMED-Plus investigators
Publicada:
1 nov 2020
Ahead of Print:
13 jun 2020
Resumen:
Introduction and objectives: Metabolic syndrome (MetS) is a combination of various cardiovascular risk factors with a major impact on morbidity and premature mortality. However, the impact of MetS on self-reported health-related quality of life (HRQoL) is unknown. This study evaluated the HRQoL in a Spanish adult population aged 55 years and older with MetS. Method: A cross-sectional analysis was performed with baseline data from the PREDIMED-Plus multicentre randomized trial. The participants were 6430 men and women aged 55-75 years with overweight/obesity (body mass index >= 27 and <= 40 kg/m(2)) and MetS. The SF-36 questionnaire was used as a tool to measure HRQoL. Scores were calculated on each scale of the SF-36 by gender and age.
Results: Participants showed higher scores in the social function (mean 85.9, 95% CI; 85.4-86.4) and emotional role scales (mean 86.8, 95% CI; 86.0-87.5). By contrast, the worst scores were obtained in the aggregated physical dimensions. In addition, men obtained higher scores than women on all scales. Among men, the worst score was obtained in general health (mean 65.6, 95% CI; 65.0-66.2), and among women, in body pain (mean 54.3, 95%Cl; 53.4-55.2). A significant decrease was found in the aggregated physical dimensions score among participants 70-75 years old, but an increased one in the aggregated mental dimensions, compared to younger participants. Conclusions: Our results reflect that the MetS may negatively affect HRQoL in the aggregated physical dimensions, body pain in women, and general health in men. However, this adverse association was absent for the psychological dimensions of HRQoL, which were less affected. (C) 2020 Sociedad Espanola de Medicos de Atencion Primaria (SEMERGEN). Published by Elsevier Espana, S.L.U. All rights reserved.
Filiaciones:
Marcos-Delgado A:
The Research Group in Gene - Environment and Health Interactions, IBIOMED - University of León, León, Spain
Department of Biomedical Sciences, Area of Preventive Medicine and Public Health, University of León, León, Spain
López-García E:
Bioaraba Health Research Institute
Osakidetza Basque Health Service, Araba University Hospital
University of the Basque Country UPV/EHU
Vitoria-Gasteiz, Spain
Nutritional Genomics and Epigenomics Group, IMDEA Food Institute, CEI UAM+CSIC, Madrid, Spain
Department of Preventive Medicine and Public Health, Universidad Autónoma de Madrid/ IdiPaz, Madrid, Spain
Martínez-González MA:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
University of Navarra, Department of Preventive Medicine and Public Health, IDISNA, Pamplona, Spain
Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA
Salas-Salvadó J:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Universitat Rovira i Virgili, Departament de Bioquímica i Biotecnologia, Unitat de Nutrició, Reus, Spain
University Hospital of Sant Joan de Reus, Nutrition Unit, Reus, Spain
Institut d'Investigació Sanitària Pere Virgili (IISPV), Reus, Spain
:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Department of Preventive Medicine, University of Valencia, Valencia, Spain
Fitó M:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Unit of Cardiovascular Risk and Nutrition, Institut Hospital del Mar de Investigaciones Médicas Municipal d'Investigació Mèdica (IMIM), Barcelona, Spain
Romaguera D:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Health Research Institute of the Balearic Islands (IdISBa), Palma de Mallorca, Spain
Vioque J:
CIBER de Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain
Miguel Hernandez University, ISABIAL-FISABIO, Alicante, Spain
Alonso-Gómez AM:
Bioaraba Health Research Institute
Osakidetza Basque Health Service, Araba University Hospital
University of the Basque Country UPV/EHU
Vitoria-Gasteiz, Spain
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Wärnberg J:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Department of Nursing, School of Health Sciences, University of Málaga-Institute of Biomedical Research in Malaga (IBIMA), Málaga, Spain
Martínez JA:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Department of Nutrition, Food Sciences, and Physiology, Center for Nutrition Research, University of Navarra, Pamplona, Spain
Cardiometabolic Nutrition Group, IMDEA Food, CEI UAM + CSIC, Madrid, Spain
Serra-Majem L:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Nutrition Research Group, Research Institute of Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain
Estruch R:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Department of Internal Medicine, IDIBAPS, Hospital Clinic, University of Barcelona, Barcelona, Spain
Fernández-García JC:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Virgen de la Victoria Hospital, Department of Endocrinology, Instituto de Investigación Biomédica de Málaga (IBIMA). University of Málaga, Málaga, Spain
Lapetra J:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Department of Family Medicine, Research Unit, Distrito Sanitario Atención Primaria Sevilla, Sevilla, Spain
Pintó X:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Lipids and Vascular Risk Unit, Internal Medicine, Hospital Universitario de Bellvitge-IDIBELL, Hospitalet de Llobregat, Barcelona, Spain
University of Barcelona, Spain
Tur JA:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Health Research Institute of the Balearic Islands (IdISBa), Palma de Mallorca, Spain
Research Group on Community Nutrition & Oxidative Stress, University of Balearic Islands, Palma de Mallorca, Spain
López-Miranda J:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Department of Internal Medicine, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, Cordoba, Spain
Cano-Ibañez N:
CIBER de Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain
Department of Preventive Medicine and Public Health, University of Granada, Granada, Spain
Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA), Granada, Spain
Delgado-Rodríguez M:
Department of Nursing, School of Health Sciences, University of Málaga-Institute of Biomedical Research in Malaga (IBIMA), Málaga, Spain
Division of Preventive Medicine, Faculty of Medicine, University of Jaén, Jaén, Spain
Matía-Martín P:
Department of Endocrinology and Nutrition, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdISSC), Madrid, Spain
Daimiel L:
Nutritional Genomics and Epigenomics Group, IMDEA Food Institute, CEI UAM+CSIC, Madrid, Spain
Carriedo E:
Centro de Salud de José Aguado. Gerencia de Atención Primaria de León
Vidal J:
Department of Endocrinology, Institut d'Investigacions Biomédiques August Pi Sunyer (IDIBAPS), Hospital Clinic, University of Barcelona, Barcelona, Spain
CIBER Diabetes y enfermedades metabólicas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Madrid, Spain
Vázquez C:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Department of Endocrinology, Fundación Jiménez-Díaz, Madrid, Spain
Ros E:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Lipid Clinic, Department of Endocrinology and Nutrition, Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Hospital Clínic, Barcelona, Spain
Lozano-Oloriz E:
University of Navarra, Department of Preventive Medicine and Public Health, IDISNA, Pamplona, Spain
Bulló M:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Universitat Rovira i Virgili, Departament de Bioquímica i Biotecnologia, Unitat de Nutrició, Reus, Spain
Institut d'Investigació Sanitària Pere Virgili (IISPV), Reus, Spain
:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Department of Preventive Medicine, University of Valencia, Valencia, Spain
Zomeño MD:
Unit of Cardiovascular Risk and Nutrition, Institut Hospital del Mar de Investigaciones Médicas Municipal d'Investigació Mèdica (IMIM), Barcelona, Spain
Blanquerna, School of Health Sciences, Universitat Ramon Llull, Barcelona
Fiol M:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Health Research Institute of the Balearic Islands (IdISBa), Palma de Mallorca, Spain
González-Palacios S:
CIBER de Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain
Miguel Hernandez University, ISABIAL-FISABIO, Alicante, Spain
Sorto-Sánchez C:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Bioaraba Health Research Institute
Osakidetza Basque Health Service, Araba University Hospital
University of the Basque Country UPV/EHU
Vitoria-Gasteiz, Spain
Pérez-Farinós N:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Departament of Public Health, University of Málaga-Institute of Biomedical Research in Málaga (IBIMA), Málaga, Spain
Goñi-Ruiz N:
University of Navarra, Department of Preventive Medicine and Public Health, IDISNA, Pamplona, Spain
Sanchez-Villegas A:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Nutrition Research Group, Research Institute of Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain
Muñoz-Garach A:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Virgen de la Victoria Hospital, Department of Endocrinology, Instituto de Investigación Biomédica de Málaga (IBIMA). University of Málaga, Málaga, Spain
Hospital Virgen de las Nieves de Granada, Departament of Endocrinology and Nutrition
Santos-Lozano JM:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Lipids and Vascular Risk Unit, Internal Medicine, Hospital Universitario de Bellvitge-IDIBELL, Hospitalet de Llobregat, Barcelona, Spain
Departament of Medicine, University of Sevilla, Sevilla, Spain
Galera A:
Lipids and Vascular Risk Unit, Internal Medicine, Hospital Universitario de Bellvitge-IDIBELL, Hospitalet de Llobregat, Barcelona, Spain
Bouzas C:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Health Research Institute of the Balearic Islands (IdISBa), Palma de Mallorca, Spain
Research Group on Community Nutrition & Oxidative Stress, University of Balearic Islands, Palma de Mallorca, Spain
Toledo E:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
University of Navarra, Department of Preventive Medicine and Public Health, IDISNA, Pamplona, Spain
Babio N:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Universitat Rovira i Virgili, Departament de Bioquímica i Biotecnologia, Unitat de Nutrició, Reus, Spain
Institut d'Investigació Sanitària Pere Virgili (IISPV), Reus, Spain
González JI:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Department of Preventive Medicine, University of Valencia, Valencia, Spain
Del Val-García JL:
Institut Català de la Salut and IDIAP Jordi Gol, Barcelona, Spain
Moñino M:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Health Research Institute of the Balearic Islands (IdISBa), Palma de Mallorca, Spain
Martínez-Vergaran MC:
CIBER de Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain
Miguel Hernandez University, ISABIAL-FISABIO, Alicante, Spain
Goicolea-Güemez L:
Bioaraba Health Research Institute
Osakidetza Basque Health Service, Araba University Hospital
University of the Basque Country UPV/EHU
Vitoria-Gasteiz, Spain
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Galilea-Zabalza I:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Basora J:
Centro de Investigación Biomédica en Red Fisiopatologia de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain
Universitat Rovira i Virgili, Departament de Bioquímica i Biotecnologia, Unitat de Nutrició, Reus, Spain
Lipid Clinic, Department of Endocrinology and Nutrition, Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Hospital Clínic, Barcelona, Spain
Institut Català de la Salut and IDIAP Jordi Gol, Barcelona, Spain
Muñoz MA:
Unitat de Suport a la Recerca de Barcelona. IDIAPJGol. Gerencia de Atención Primaria de Barcelona. Institut Català de la Salut, Barcelona
Builf P:
University of Navarra, Department of Preventive Medicine and Public Health, IDISNA, Pamplona, Spain
Fernández-Villa T:
The Research Group in Gene - Environment and Health Interactions, IBIOMED - University of León, León, Spain
Department of Biomedical Sciences, Area of Preventive Medicine and Public Health, University of León, León, Spain
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