Strongyloidiasis in Southern Alicante (Spain): Comparative Retrospective Study of Autochthonous and Imported Cases
Por:
Lucas Dato A, Pacheco-Tenza MI, Borrajo Brunete E, Martínez López B, García López M, González Cuello I, Gregori Colomé J, Navarro Cots M, Saugar JM, García-Vazquez E, Ruiz-Maciá JA and Llenas-García J
Publicada:
1 ago 2020
Ahead of Print:
23 jul 2020
Resumen:
Background: Strongyloidiasis is a parasitic disease with global prevalence. In Spain, autochthonous cases are concentrated in the Mediterranean basin. We aimed to analyze clinical and epidemiological characteristics ofStrongyloides stercoralisinfection in Vega Baja del Segura (Spain), comparing autochthonous versus imported cases. Methods: Observational retrospective study of all strongyloidiasis cases from January 2009 to January 2019. Cases were diagnosed by stool larvae visualization, positive culture, PCR,Strongyloidesserology, and/or compatible histology. Results: We included 36 patients (21 men) with a mean age of 60.8 years +/- 17.6; 15 cases were autochthonous and 21 imported 80.9% from Latin America. Autochthonous cases were associated with older age (mean 71.3 vs. 53.3 years;p= 0.002), male sex (odds ratio (OR) 5.33; 95% confidence interval (CI) 1.15-24.68;p= 0.041), and agricultural activity (OR 13.5; 95% CI 2.4-73.7;p= 0.002). Fourteen were asymptomatic, three autochthonous cases presented with hyperinfection syndrome, and two patients died. There was no difference between autochthonous versus imported origin in eosinophilia at diagnosis (93.3% vs. 75%;p= 0.207), treatment received, or clinical response (85.7% vs. 88.9% cured;p= 1). Conclusion: In our region, imported strongyloidiasis coexists with autochthonous cases, which are mainly in older male farmers who are diagnosed at more advanced stages. Systematic screening programs are needed.
Filiaciones:
:
Internal Medicine Department, Hospital Vega Baja, 03314 Orihuela, Spain
Foundation for the Promotion of Health and Biomedical Research of Valencia Region (FISABIO), 46020 Valencia, Spain
Pacheco-Tenza MI:
Internal Medicine Department, Hospital Clínico Universitario Virgen de la Arrixaca, 30120 Murcia, Spain
:
Foundation for the Promotion of Health and Biomedical Research of Valencia Region (FISABIO), 46020 Valencia, Spain
Microbiology Department, Hospital Vega Baja, 03314 Orihuela, Spain
:
Internal Medicine Department, Hospital Vega Baja, 03314 Orihuela, Spain
Foundation for the Promotion of Health and Biomedical Research of Valencia Region (FISABIO), 46020 Valencia, Spain
:
Internal Medicine Department, Hospital Vega Baja, 03314 Orihuela, Spain
Foundation for the Promotion of Health and Biomedical Research of Valencia Region (FISABIO), 46020 Valencia, Spain
:
Internal Medicine Department, Hospital Vega Baja, 03314 Orihuela, Spain
Foundation for the Promotion of Health and Biomedical Research of Valencia Region (FISABIO), 46020 Valencia, Spain
:
Internal Medicine Department, Hospital Vega Baja, 03314 Orihuela, Spain
Foundation for the Promotion of Health and Biomedical Research of Valencia Region (FISABIO), 46020 Valencia, Spain
:
Foundation for the Promotion of Health and Biomedical Research of Valencia Region (FISABIO), 46020 Valencia, Spain
Microbiology Department, Hospital Vega Baja, 03314 Orihuela, Spain
Saugar JM:
Parasitology Department, Centro Nacional de Microbiología, Instituto Carlos III, 28903 Madrid, Spain
García-Vazquez E:
Infectious Diseases Unit, Hospital Clínico Universitario Virgen de la Arrixaca, 30120 Murcia, Spain
Instituto Murciano de Investigación Biosanitaria (IMIB), Universidad de Murcia, 30120 Murcia, Spain
Ruiz-Maciá JA:
Pathological Department, Hospital Clínico Universitario Virgen de la Arrixaca, 30120 Murcia, Spain
:
Internal Medicine Department, Hospital Vega Baja, 03314 Orihuela, Spain
Foundation for the Promotion of Health and Biomedical Research of Valencia Region (FISABIO), 46020 Valencia, Spain
Clinical Medicine Department, Universidad Miguel Hernández de Elche, 03202 Elche, Spain
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