Laparoscopic staged colon-first resection for metastatic colorectal cancer: Perioperative and midterm outcomes from a single-center experience
Por:
Sebastián-Tomás JC, Domingo-Del Pozo C, Gómez-Abril SÁ, Navarro-Martínez S, Ortiz-Tarín I, Torres-Sánchez T, Martínez-Blasco A and Martínez-Pérez A
Publicada:
1 dic 2020
Ahead of Print:
1 ago 2020
Resumen:
Introduction The present study aimed to evaluate the short- and mid-term outcomes of laparoscopic colon-first staged resection for colorectal cancer (CRC) and colorectal cancer liver metastases (CRCLM). Methods This study included patients with metastatic CRC who underwent laparoscopic surgical staged resection for the primary tumor and CRCLM between June 2013 and December 2018. Data collection included the baseline patient's and tumor features, the perioperative and histopathologic outcomes from both surgical procedures, and the oncologic follow-up. Results Twenty-five patients were eligible for the study. Three major and 22 minor laparoscopic liver resections were performed following laparoscopic CRC surgery. Five patients required conversion to laparotomy during CRCLM resection, but no conversion was needed for the colorectal procedures. The rate of severe intraoperative complications (CLASSIC grade III-IV) was 8% and 16% during CRC and CRCLM resection, respectively. Three patients (12%) developed major postoperative complications (Clavien-Dindo grade > III) after both interventions, including one death due to intraoperative bleeding. During a median follow-up of 30 months, 15 patients were diagnosed with disease recurrence. The 3-year disease-free survival and overall survival were 33.3% and 73.9%, respectively. Conclusions Laparoscopic staged resection for CRC and CRCLM is safe, feasible, and offers acceptable midterm oncological outcomes in patients with metastatic colorectal cancer.
Filiaciones:
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Department of General and Digestive Surgery, Hospital Universitario Doctor Peset, Valencia, Spain
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Department of General and Digestive Surgery, Hospital Universitario Doctor Peset, Valencia, Spain
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Department of General and Digestive Surgery, Hospital Universitario Doctor Peset, Valencia, Spain
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Department of General and Digestive Surgery, Hospital Universitario Doctor Peset, Valencia, Spain
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Department of General and Digestive Surgery, Hospital Universitario Doctor Peset, Valencia, Spain
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Department of General and Digestive Surgery, Hospital Universitario Doctor Peset, Valencia, Spain
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Department of General and Digestive Surgery, Hospital Universitario Doctor Peset, Valencia, Spain
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Department of General and Digestive Surgery, Hospital Universitario Doctor Peset, Valencia, Spain
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