Imported cysticercosis in Spain: A retrospective case series from the plus REDIVI Collaborative Network
Por:
Herrador Z, Pérez-Molina JA, Henríquez Camacho CA, Rodriguez-Guardado A, Bosch-Nicolau P, Calabuig E, Domínguez-Castellano A, Pérez-Jacoiste MA, Ladrón de Guevara MC, Mena A, Ruiz-Giardin JM, Torrús D, Wikman-Jorgensen P, Benito A and López-Vélez R
Publicada:
1 sep 2020
Ahead of Print:
23 abr 2020
Resumen:
Background: Neurocysticercosis (NCC) is the most common parasitic neurological disease worldwide and a major cause of epilepsy. Spain is the country reporting the highest number of NCC imported cases in Europe.
Methodology: Retrospective case series of NCC patients registered in the +REDIVI Network from October 1, 2009 to July 2018. A specific questionnaire, including clinical and diagnostic characteristics, was created and sent to the collaborator centers.
Results: 46 cases were included in the analysis. 55% were male, mean age of 40 years. 95.6% were migrants. The median duration since migration from an endemic area was 10 years. Predominant nationalities were Ecuadorians (50%) and Bolivians (30.4%). Frequent locations were parenchymal (87%), subarachnoid (26.1%) and intraventricular cysts (10.9%). Serological analysis was performed in 91.3%, being 54.8% positive. Most prevalent clinical manifestations were persistent headache (60.9%), epilepsy (43.5%) and visual changes (13%). Patients were mainly treated with albendazole (76.1%), corticosteroids (67.4%), and anticonvulsionants (52.2%). 82.5% had a favorable clinical outcome.
Conclusions: Most NCC cases were long-standing migrants. Few clinical differences were observed depending on the cysticerci location. The treatment was often not according to current recommendations, and no uniform criteria were followed when it came to the therapeutic regimen. NCC case management in Spain (including clinician awareness and laboratory capacity improvements) needs to be strengthened.
Filiaciones:
Herrador Z:
Centro Nacional de Medicina Tropical, Instituto de Salud Carlos III, Madrid, Spain
Network Biomedical Research on Tropical Diseases (RICET in Spanish), Madrid, Spain
Pérez-Molina JA:
Network Biomedical Research on Tropical Diseases (RICET in Spanish), Madrid, Spain
National Referral Unit for Tropical Diseases, Infectious Diseases Department, Hospital Universitario Ramón y Cajal, IRICYS, Madrid, Spain
Henríquez Camacho CA:
National Referral Unit for Tropical Diseases, Infectious Diseases Department, Hospital Universitario Ramón y Cajal, IRICYS, Madrid, Spain
Rodriguez-Guardado A:
Hospital Universitario de Cabueñes, Gijón, Spain
Bosch-Nicolau P:
Hospital Universitario de Vall d'Hebron, Barcelona, Spain
Calabuig E:
Hospital Universitario La Fe, Valencia, Spain
Domínguez-Castellano A:
Hospital Universitario de Virgen Macarena, Sevilla, Spain
Pérez-Jacoiste MA:
Hospital Universitario 12 de Octubre, Madrid, Spain
Ladrón de Guevara MC:
Hospital Universitario La Paz University Hospital, Madrid, Spain
Mena A:
Hospital Universitario Son Espases, Palma Mallorca, Spain
Ruiz-Giardin JM:
Hospital Universitario de Fuenlabrada, Madrid, Spain
Torrús D:
Hospital Universitario de Alicante, Alicante, Spain
:
Medicina Interna. Hospital Universitario de Elda, Alicante, Spain
Foundation for the Promotion of Health and Biomedical Research of Valencia Region, FISABIO, Spain
Benito A:
Centro Nacional de Medicina Tropical, Instituto de Salud Carlos III, Madrid, Spain
Network Biomedical Research on Tropical Diseases (RICET in Spanish), Madrid, Spain
López-Vélez R:
Network Biomedical Research on Tropical Diseases (RICET in Spanish), Madrid, Spain
National Referral Unit for Tropical Diseases, Infectious Diseases Department, Hospital Universitario Ramón y Cajal, IRICYS, Madrid, Spain
Green Published, hybrid
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