Association Between Lifestyle and Hypertriglyceridemic Waist Phenotype in the PREDIMED-Plus Study
Por:
Fern?ndez-Garc?a, J, Mu?oz-Garach, A, Mart?nez-Gonz?lez, M, Salas-Salvado, J, Corella, D, Hern?ez, A, Romaguera, D, Vioque, J, Alonso-G?mez, A, W?rnberg, J, Mart?nez, J, Serra-Majem, L, Estruch, R, Lapetra, J, Pint?, X, Tur, J, Garcia-Rios, A, Molina, L, Gaforio, J, Mat?a-Mart?n, P, Daimiel, L, S?nchez, V, Vidal, J, Prieto, L, Ros, E, Go?i, N, Babio, N, Ortega-Azorin, C, Casta?er, O, Konieczna, J, Barandiaran, L, Vaquero-Luna, J, Benavente-Mar?n, J, Zulet, M, Sanchez-Villegas, A, Sacanella, E, Huelgas, R, Mir?-Moriano, L, Gimenez-Gracia, M, Julibert, A, Razquin, C, Basora, J, Portol?s, O, Goday, A, Galm?s-Panad?s, A, L?pez-Garc?a, C, Moreno-Rodriguez, A, Toledo, E, D?az-L?pez, A, Fit?, M, Tinahones, F, Bernal-L?pez, M and PREDIMED-Plus Investigators
Publicada:
1 mar 2020
Resumen:
Objective The hypertriglyceridemic waist (HTGW) phenotype is characterized by abdominal obesity and high levels of triglycerides. In a cross-sectional assessment of PREDIMED-Plus trial participants at baseline, HTGW phenotype prevalence was evaluated, associated risk factors were analyzed, and the lifestyle of individuals with metabolic syndrome and HTGW was examined.
Methods A total of 6,874 individuals aged 55 to 75 with BMI >= 27 and < 40 kg/m(2) were included and classified by presence (HTGW(+)) or absence (HTGW(-)) of HTGW (waist circumference: men >= 102 cm, women >= 88 cm; fasting plasma triglycerides >= 150 mg/dL). Analytical parameters and lifestyle (energy intake and expenditure) were analyzed.
Results A total of 38.2% of the sample met HTGW(+) criteria. HTGW(+) individuals tended to be younger, have a greater degree of obesity, be sedentary, and be tobacco users. They had higher peripheral glucose, total cholesterol, and low-density lipoprotein cholesterol levels; had lower high-density lipoprotein cholesterol levels; and had increased prevalence of type 2 diabetes mellitus. Mediterranean diet (MedDiet) adherence and physical activity were greater in HTGW(-) patients. Age, BMI, tobacco use, total energy expenditure, hypertension, type 2 diabetes mellitus, and MedDiet adherence were associated with HTGW(+).
Conclusions HTGW is a highly prevalent phenotype in this population associated with younger age, higher BMI, tobacco use, and decreased MedDiet adherence. HTGW(-) individuals were more physically active with greater total physical activity, and fewer had hypertension.
Filiaciones:
Fern?ndez-Garc?a, J:
Malaga Univ, Virgen de la Victoria Univ Hosp, Dept Endocrinol & Nutr, Inst Invest Biomed Malaga IBIMA, Malaga, Spain
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Mu?oz-Garach, A:
Malaga Univ, Virgen de la Victoria Univ Hosp, Dept Endocrinol & Nutr, Inst Invest Biomed Malaga IBIMA, Malaga, Spain
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Mart?nez-Gonz?lez, M:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Univ Navarra, Dept Prevent Med & Publ Hlth, IDISNA, Pamplona, Spain
Harvard TH Chan Sch Publ Hlth, Dept Nutr, Boston, MA USA
Salas-Salvado, J:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Univ Rovira & Virgili, Dept Bioquim & Biotecnol, Reus, Spain
Univ Hosp St Joan Reus, Nutr Unit, Reus, Spain
IISPV, Reus, Spain
:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Univ Valencia, Dept Prevent Med, Valencia, Spain
Hern?ez, A:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Hosp Clin Barcelona, Inst Invest Biomed August Pi Sunyer IDIBAPS, Dept Internal Med, Barcelona, Spain
Univ Ramon Llull, Blanquerna, Sch Hlth Sci Org, Barcelona, Spain
Romaguera, D:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Hlth Res Inst Balearic Isl IdISBa, Palma De Mallorca, Spain
Vioque, J:
Inst Salud Carlos III, CIBERESP, Madrid, Spain
Miguel Hernandez Univ, ISABIAL FISABIO, Alicante, Spain
Alonso-G?mez, A:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Univ Hosp Araba, Dept Cardiol, Org Sanitaria Integrada OSI ARABA, Vitoria, Spain
Univ Basque Country UPV EHU, Vitoria, Spain
W?rnberg, J:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Univ Malaga, Dept Nursing, Sch Hlth Sci, Inst Invest Biomed Malaga IBIMA, Malaga, Spain
Mart?nez, J:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Univ Navarra, Dept Nutr Food Sci & Physiol, Ctr Nutr Res, Pamplona, Spain
CEI UAM CSIC, IMDEA Food, Cardiometab Nutr Grp, Madrid, Spain
Serra-Majem, L:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Univ Las Palmas Gran Canaria, Nutr Res Grp, Res Inst Biomed & Hlth Sci IUIBS, Las Palmas Gran Canaria, Spain
Estruch, R:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Hosp Clin Barcelona, Inst Invest Biomed August Pi Sunyer IDIBAPS, Dept Internal Med, Barcelona, Spain
Univ Barcelona, Barcelona, Spain
Lapetra, J:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Dist Sanitario Atenc Primaria Sevilla, Dept Family Med, Res Unit, Seville, Spain
Pint?, X:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Univ Barcelona, Barcelona, Spain
Hosp Univ Bellvitge IDIBELL, Lipids & Vasc Risk Unit, Internal Med, Barcelona, Spain
Tur, J:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Univ Balearic Isl, Res Grp Community Nutr & Oxidat Stress, Palma de Mallorca, Spain
Garcia-Rios, A:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Univ Cordoba, Reina Sofia Univ Hosp, Dept Internal Med, Maimonides Biomed Res Inst Cordoba IMIBIC, Cordoba, Spain
Molina, L:
Inst Salud Carlos III, CIBERESP, Madrid, Spain
Univ Granada, Dept Prevent Med & Publ Hlth, Granada, Spain
Gaforio, J:
Inst Salud Carlos III, CIBERESP, Madrid, Spain
Univ Jaen, Fac Med, Div Prevent Med, Jaen, Spain
Mat?a-Mart?n, P:
Inst Invest Sanitaria Hosp Clin San Carlos IdISSC, Dept Endocrinol & Nutr, Madrid, Spain
Daimiel, L:
CEI UAM CSIC, Nutr Genom & Epigen Grp, IMDEA Food, Madrid, Spain
S?nchez, V:
Inst Salud Carlos III, CIBERESP, Madrid, Spain
Univ Leon, Inst Biomed IBIOMED, Leon, Spain
Vidal, J:
ISCIII, CIBERDEM, Madrid, Spain
Univ Barcelona, Hosp Clin, Inst Invest Biomed August Pi Sunyer IDIBAPS, Dept Endocrinol, Barcelona, Spain
Prieto, L:
Fdn Jimenez Diaz, Dept Endocrinol, Madrid, Spain
Ros, E:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Hosp Clin Barcelona, Inst Invest Biomed August Pi Sunyer IDIBAPS, Lipid Clin, Dept Endocrinol & Nutr, Barcelona, Spain
Go?i, N:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Univ Navarra, Dept Prevent Med & Publ Hlth, IDISNA, Pamplona, Spain
Babio, N:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Univ Rovira & Virgili, Dept Bioquim & Biotecnol, Reus, Spain
Univ Hosp St Joan Reus, Nutr Unit, Reus, Spain
IISPV, Reus, Spain
Ortega-Azorin, C:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Univ Valencia, Dept Prevent Med, Valencia, Spain
Casta?er, O:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Inst Hosp del Mar Invest Med Municipal Invest Med, Unit Cardiovasc Risk & Nutr, Barcelona, Spain
Konieczna, J:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Hlth Res Inst Balearic Isl IdISBa, Palma De Mallorca, Spain
Barandiaran, L:
Inst Salud Carlos III, CIBERESP, Madrid, Spain
Miguel Hernandez Univ, ISABIAL FISABIO, Alicante, Spain
Vaquero-Luna, J:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Univ Hosp Araba, Dept Cardiol, Org Sanitaria Integrada OSI ARABA, Vitoria, Spain
Benavente-Mar?n, J:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Univ Malaga, Dept Nursing, Sch Hlth Sci, Inst Invest Biomed Malaga IBIMA, Malaga, Spain
Zulet, M:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Univ Navarra, Dept Nutr Food Sci & Physiol, Ctr Nutr Res, Pamplona, Spain
Sanchez-Villegas, A:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Univ Las Palmas Gran Canaria, Nutr Res Grp, Res Inst Biomed & Hlth Sci IUIBS, Las Palmas Gran Canaria, Spain
Sacanella, E:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Hosp Clin Barcelona, Inst Invest Biomed August Pi Sunyer IDIBAPS, Dept Internal Med, Barcelona, Spain
Univ Barcelona, Barcelona, Spain
Huelgas, R:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Reg Univ Hosp Malaga, Dept Internal Med, Inst Invest Biomed Malaga IBIMA, Malaga, Spain
Mir?-Moriano, L:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Dist Sanitario Atenc Primaria Sevilla, Dept Family Med, Res Unit, Seville, Spain
Gimenez-Gracia, M:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Hosp Univ Bellvitge IDIBELL, Lipids & Vasc Risk Unit, Internal Med, Barcelona, Spain
Julibert, A:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Hlth Res Inst Balearic Isl IdISBa, Palma De Mallorca, Spain
Univ Balearic Isl, Res Grp Community Nutr & Oxidat Stress, Palma de Mallorca, Spain
Razquin, C:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Univ Navarra, Dept Prevent Med & Publ Hlth, IDISNA, Pamplona, Spain
Harvard TH Chan Sch Publ Hlth, Dept Nutr, Boston, MA USA
Basora, J:
Univ Rovira & Virgili, Dept Bioquim & Biotecnol, Reus, Spain
IISPV, Reus, Spain
Portol?s, O:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Univ Valencia, Dept Prevent Med, Valencia, Spain
Goday, A:
Univ Barcelona, Barcelona, Spain
Inst Hosp del Mar Invest Med Municipal Invest Med, Unit Cardiovasc Risk & Nutr, Barcelona, Spain
Galm?s-Panad?s, A:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Hlth Res Inst Balearic Isl IdISBa, Palma De Mallorca, Spain
:
Ctr Salud Raval Elche, Alicante, Spain
Moreno-Rodriguez, A:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Univ Hosp Araba, Dept Cardiol, Org Sanitaria Integrada OSI ARABA, Vitoria, Spain
Toledo, E:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Univ Navarra, Dept Prevent Med & Publ Hlth, IDISNA, Pamplona, Spain
Harvard TH Chan Sch Publ Hlth, Dept Nutr, Boston, MA USA
D?az-L?pez, A:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Univ Rovira & Virgili, Dept Bioquim & Biotecnol, Reus, Spain
Univ Hosp St Joan Reus, Nutr Unit, Reus, Spain
IISPV, Reus, Spain
Fit?, M:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Inst Hosp del Mar Invest Med Municipal Invest Med, Unit Cardiovasc Risk & Nutr, Barcelona, Spain
Tinahones, F:
Malaga Univ, Virgen de la Victoria Univ Hosp, Dept Endocrinol & Nutr, Inst Invest Biomed Malaga IBIMA, Malaga, Spain
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Bernal-L?pez, M:
Inst Hlth Carlos III, Ctr Invest Biomedica Red Fisiopatol Obesidad & Nu, Madrid, Spain
Reg Univ Hosp Malaga, Dept Internal Med, Inst Invest Biomed Malaga IBIMA, Malaga, Spain
Green Accepted
|