Computerized cognitive remediation therapy, REHACOM, in first episode of schizophrenia: A randomized controlled trial
Por:
García-Fernández L, Cabot-Ivorra N, Rodríguez-García V, Pérez-Martín J, Dompablo M, Pérez-Gálvez B and Rodriguez-Jimenez R
Publicada:
1 nov 2019
Resumen:
Patients with schizophrenia show cognitive impairments that have been linked to poor social functioning. Computerized cognitive remediation therapy has shown to be effective in improving both cognition and functioning in chronic schizophrenia, but relatively little is known about how these approaches improve cognition and functioning when applied to early stages of psychosis. Eighty-six participants with a first episode of psychosis, undergoing a specific program for early stages of schizophrenia, undertook either the REHACOM computerized cognitive remediation intervention (n = 36), or an active control condition (n = 50) consisting in 24 one-hour sessions addressed twice a week. Clinical features, cognition and functioning were assessed at baseline, post-treatment and six months after finishing the intervention. A significant progressive improvement in neurocognition and functioning was globally shown with no differences observed between the experimental and control group at post training or follow up. All cognitive domains but Social Cognition improved between 0.5 and 1 S.D. through the study period. The computerized cognitive remediation therapy REHACOM has not proved to be effective on improving cognition nor functioning compared to controls in outpatients with a first episode of schizophrenia.
Filiaciones:
:
Department of Clinical Medicine, Universidad Miguel Hernández, Edificio Muhammad Al-Shafra, Campus de San Juan, Ctra. De Valencia, Km 87, 03550 San Juan, Alicante, Spain
Department of Psychiatry, Hospital Universitario de San Juan, Alicante, Ctra. Nacional. 332, s/n, 03550 San Juan, Alicante, Spain
CIBERSAM (Biomedical Research Networking Centre in Mental Health), Spain
Cabot-Ivorra N:
Doctoral School, Universidad Católica de Valencia San Vicente Mártir, C/Guillem de Castro, 65 bajo, 46008 Valencia, Spain
:
Department of Psychiatry, Hospital Universitario de San Juan, Alicante, Ctra. Nacional. 332, s/n, 03550 San Juan, Alicante, Spain
Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, KCL.16 De Crespigny Park, Camberwell, London SE5 8AF, UK
:
Department of Psychiatry, Hospital Universitario de San Juan, Alicante, Ctra. Nacional. 332, s/n, 03550 San Juan, Alicante, Spain
Dompablo M:
CIBERSAM (Biomedical Research Networking Centre in Mental Health), Spain
Department of Psychiatry, Instituto de Investigación Sanitaria Hospital, 12 de Octubre (imas 12), Av. Córdoba s/n, 28041, Madrid, Spain
:
Department of Clinical Medicine, Universidad Miguel Hernández, Edificio Muhammad Al-Shafra, Campus de San Juan, Ctra. De Valencia, Km 87, 03550 San Juan, Alicante, Spain
Rodriguez-Jimenez R:
CIBERSAM (Biomedical Research Networking Centre in Mental Health), Spain
Department of Psychiatry, Instituto de Investigación Sanitaria Hospital, 12 de Octubre (imas 12), Av. Córdoba s/n, 28041, Madrid, Spain
CogPsy-Group, Universidad Complutense (UCM), Madrid, Spain
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