Pertussis in adults with persistent cough: a prospective follow up study in primary care.
Por:
Puig-Barbera, J, Diez-Domingo, J, Pastor-Villalba, E, Garcia-Lomas, J, Huertas-Zarco, I and Perez-Hoyose, S
Publicada:
1 ene 2009
Resumen:
Despite high coverage of pertussis vaccine, B. pertussis has remained endemic and adults are recognized as reservoir for infection among incompletely immunized infants. Between November 15th 2004 and November 14th 2006, 37 general practitioners, attending 56,658 adults, recruited all patients with persistent cough. A diagnosis of pertussis was considered in those with an unexplained cough, lasting 14 or more days and a positive polymerase chain reaction (PCR) or enzyme-linked immunosorbent assay (ELISA) IgG anti-Pertussis Toxin (PT). During the period of the study 86 patients presented with persistent cough (106 cases per 100,000 person-years). According to laboratory criteria, 35% were classified as associated to B. pertussis, with an incidence of 34 cases per 100,000 person-years (95% CI 23 to 46 per 100,000 person-years). (C) 2009 Elsevier B. V. All rights reserved
Filiaciones:
:
Ctr Salud Publ Castellon, Avda Mar 12, Castellon de La Plana 12003, Spain
Ctr Super Investigac & Salud Publica, Valencia 46020, Spain
:
Ctr Super Investigac & Salud Publica, Valencia 46020, Spain
:
Direcc Gen Salud Publica, Valencia 46020, Spain
Garcia-Lomas, J:
Univ Valencia, Sch Med, Valencia 46010, Spain
:
Direcc Gen Salud Publica, Valencia 46020, Spain
Perez-Hoyose, S:
Barcelona Ctr, Barcelona 08036, Spain
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