Smoking may increase the risk of hospitalization due to influenza
Por:
Godoy P, Castilla J, Mayoral JM, Delgado-Rodríguez M, Martín V, Astray J, Soldevila N, González-Candelas F, Castro A, Baricot M, Tamames S, Alonso J, Galán JC, Quintana JM, Pumarola T and Domínguez A
Publicada:
1 oct 2016
Categoría:
Public health, environmental and occupational health
Resumen:
Background: Smoking may facilitate influenza virus infections and their severity. The objective was to investigate the risk of hospitalization due to influenza in Spanish smokers and ex-smokers. Methods: We carried out a multicentre, case-control study in 2011. Cases [patients a parts per thousand yen 18 years hospitalized > 24 h with real time polymerase chain reaction (RT-PCR)-confirmed influenza] were selected from 29 Spanish hospitals. For each case, we selected an outpatient aged a parts per thousand yen 18 years with RT-PCR-confirmed influenza matched by age (+/- 5 years), date of hospitalization of the case (+/- 10 days) and province of residence. We collected epidemiological variables, comorbidities and the smoking history. The risk of hospitalization due to smoking was determined by the adjusted odds ratio (aOR) using logistic regression. Results: We studied 471 hospitalized cases and 476 outpatient cases. Hospitalized cases had a higher frequency of influenza risk factors compared with outpatient cases. Hospitalized cases had a higher frequency of smoking (30.9% vs. 17.1%) and being ex-smokers (29.3% vs. 25.3%). Current smoking (aOR = 2.18, 95% CI: 1.23-3.87) and being an ex-smoker (aOR = 1.73, 95% CI: 1.07-2.82) were associated with the risk of hospitalization. Conclusions: Smoking may increase the risk of hospitalization in smokers and ex-smokers when infected by the influenza virus. Smoking prevention could reduce hospitalizations. Influenza vaccination is recommended for smokers.
Filiaciones:
Godoy P:
Department of Health, Generalitat of Catalonia, Lleida, Spain
CIBER Epidemiology and Public Health, Madrid, Spain
IRBLleida. University of Lleida, Lleida, Spain
Castilla J:
CIBER Epidemiology and Public Health, Madrid, Spain
Public Health Institute, Navarra Institute for Health Research (IdiSNA), Pamplona, Spain
Mayoral JM:
Epidemiological Surveillance Service. Andalusian Government, Sevilla, Spain
Delgado-Rodríguez M:
CIBER Epidemiology and Public Health, Madrid, Spain
University of Jaen, Jaen, Spain
Martín V:
CIBER Epidemiology and Public Health, Madrid, Spain
Grupo de Investigación en Interacciones gen-ambiente-salud. Universidad de León, León, Spain
Astray J:
Area of Epidemiology, Community of Madrid, Spain
Soldevila N:
CIBER Epidemiology and Public Health, Madrid, Spain
:
CIBER Epidemiology and Public Health, Madrid, Spain
FISABIO-CSISP, University of Valencia, Valencia, Spain
Castro A:
CIBER Respiratory Diseases, Madrid, Spain
Baricot M:
CIBER Epidemiology and Public Health, Madrid, Spain
Tamames S:
Ministry of Health, Government of Castile and Leon, Valladolid, Spain
Alonso J:
CIBER Epidemiology and Public Health, Madrid, Spain
IMIM - Hospital del Mar Medical Research Institute, Barcelona, Spain
Galán JC:
CIBER Epidemiology and Public Health, Madrid, Spain
University Hospital Ramón y Cajal, Madrid, Spain
Quintana JM:
CIBER Epidemiology and Public Health, Madrid, Spain
Research Unit, Galdakao-Usansolo hospital, San Sebastian, Spain
Pumarola T:
Spanish Network for Research in Infectious Diseases, Madrid, Spain
Domínguez A:
CIBER Epidemiology and Public Health, Madrid, Spain
Department of Public Health. University of Barcelona, Barcelona, Spain
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