Reducing test request for anti-thyroglobulin and anti-thyroid peroxidase antibodies: trends before and after interventions based on rejection rules and profile management


Por: Pellicer PS, Tamayo RG and López VN

Publicada: 1 oct 2018
Resumen:
Introduction: The objective of this study was to identify trends in requests for anti-thyroid peroxidase antibodies (TPOab) and anti-thyroglobulin antibodies (TGab) tests before and after applying set of interventions based on rejection rules and profile management. Materials and methods: Trend analysis was made at semester time intervals (from May-October 2010 to May-October 2017), before and after the intervention semester (May-October 2016). Number of tests (N) TPOab and TGab / 1000 total requests based on total N of both tests and total N of biochemical analysis laboratory requests, was calculated. To find out where the interventions had more impact we distinguished N of requests between Primary Care (PC) and Specialized Care (SC). A joinpoint regression analysis was used to determine time segments and time points in these indicators where the trend changed. Results: Trend analysis of the request of TPOab and TGab showed two clearly differentiated trend lines with a statistically significant Joinpoint (P < 0.001) with an increase in each semester from May 2010 of 7.4% and 7.5% respectively, to the semester of the interventions where there was a decrease of - 45% and - 61% located mainly in PC. Trend analysis in SC setting did not show any Joinpoint and any trend line. Conclusions: Results showed that applied interventions enabled change of trend for TPOab and TGab test requests, especially in PC where the interventions proved to be the most successful.

Filiaciones:
:
 Department of Clinical Medicine, MiBioPath group, Universidad Católica San Antonio de Murcia (UCAM), Murcia, Spain

 Unilabs Laboratory Clinical Biochemistry, Vinalopó University Hospital, Elche, Spain

:
 Unilabs Laboratory Clinical Biochemistry, Torrevieja University Hospital, Torrevieja, Spain

:
 Unit of Infectious Diseases, Vinalopó University Hospital, Elche, Spain

 Department of Clinical Medicine, MiBioPath group, Universidad Católica San Antonio de Murcia (UCAM), Murcia, Spain
ISSN: 13300962





BIOCHEMIA MEDICA
Editorial
CROATIAN SOC MEDICAL BIOCHEMISTS, Croatia, Croacia
Tipo de documento: Article
Volumen: 28 Número: 3
Páginas: 30709-30709
WOS Id: 000448275400012
ID de PubMed: 30429677
imagen gold, Green Submitted, Green Published

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