Genetic Contribution in Low Back Pain: A Prospective Genetic Association Study.
Por:
Margarit C, Roca R, Inda MD, Muriel J, Ballester P, Moreu R, Conte AL, Nuñez A, Morales D and Peiro, A
Publicada:
1 nov 2019
Ahead of Print:
1 sep 2019
Categoría:
Anesthesiology and pain medicine
Resumen:
Chronic pain is one of the most common reasons individuals seek medical attention. It is a major issue because of the wide interindividual variability in the analgesic response. This might be partly explained by the presence of variants in genes encoding molecules involved in pharmacodynamics and pharmacokinetics. The aim was to analyze opioid effectiveness in chronic low back pain (CLBP) relief after opioid titration, unveiling the impact of pharmacogenetics.
Filiaciones:
Margarit C:
Pain Unit, Department of Health of Alicante, Alicante General Hospital, Alicante, Spain
Neuropharmacology in Pain (NED) Group, Alicante Institute for Health and Biomedical Research (ISABIAL-FISABIO Foundation), Alicante, Spain
Roca R:
Neuropharmacology in Pain (NED) Group, Alicante Institute for Health and Biomedical Research (ISABIAL-FISABIO Foundation), Alicante, Spain
Inda MD:
Neuropharmacology in Pain (NED) Group, Alicante Institute for Health and Biomedical Research (ISABIAL-FISABIO Foundation), Alicante, Spain
Muriel J:
Neuropharmacology in Pain (NED) Group, Alicante Institute for Health and Biomedical Research (ISABIAL-FISABIO Foundation), Alicante, Spain
Ballester P:
Neuropharmacology in Pain (NED) Group, Alicante Institute for Health and Biomedical Research (ISABIAL-FISABIO Foundation), Alicante, Spain
Moreu R:
Clinical Pharmacology Unit, Department of Health of Alicante, Alicante General Hospital, Alicante, Spain
Conte AL:
Occupational Observatory, Miguel Hernández University of Elche, Alicante, Spain
Nuñez A:
Operations Research Center, Miguel Hernández University of Elche, Elche, Spain
Morales D:
Operational Centre, Miguel Hernandez University, Elche, Spain
Peiro, A:
Pain Unit, Department of Health of Alicante, Alicante General Hospital, Alicante, Spain
Neuropharmacology in Pain (NED) Group, Alicante Institute for Health and Biomedical Research (ISABIAL-FISABIO Foundation), Alicante, Spain
Clinical Pharmacology Unit, Department of Health of Alicante, Alicante General Hospital, Alicante, Spain
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