Air pollutant exposure during pregnancy and fetal and early childhood development. Research protocol of the INMA [Childhood and Environment Project]
Por:
Esplugues, A, Fernandez-Patier, R, Aguilera, I, Inigueza, C, Garcia Dos Santos, S, Aguirre Alfaro, A, Lacasana, M, Estarlich, M, Grimalt, J, Fernandez, M, Rebagliato, M, Sala, M, Tardon, A, Torrent, M, Dolores Martinez, M, Ribas-Fito, N, Sunyer, J and Ballester, F
Publicada:
1 mar 2007
Categoría:
Public Health, Environmental and Occupational Health
Resumen:
Introduction: The INMA (INfancia y Medio Ambiente (Spanish for Environment and Childhood]) project is a cooperative research network. This project aims to study the effects of environment and diet on fetal and early childhood development. This article aims to present the air pollutant exposure protocol during pregnancy and fetal and early childhood development of the INMA project.
Methods: The information to assess air pollutant exposure during pregnancy is based on outdoor measurement of air pollutants (nitrogen dioxide [NO2], volatile organic compounds [VOC], ozone, particulate matter [PM10, PM2.5] and of their composition (polycyclic aromatic hydrocarbons]); measurement of indoor and personal exposure (VOC and NO2); urinary measurement of a biological marker of hydrocarbon exposure (1-hydroxypyrene); and data gathered by questionnaires and geographic information systems. These data allow individual air pollutant exposure indexes to be developed, which can then be used to analyze the possible effects of exposure on fetal development and child health.
Conclusion: This protocol and the type of study allow an approximation to individual air pollutant exposure to be obtained. Finally, the large number of participants (N = 4,000), as well as their geographic and social diversity, increases the study's potential.
Filiaciones:
:
Escola Valenciana Estudis Salut, Valencia 46017, Spain
Hosp Univ La Fe, Valencia, Spain
Aguilera, I:
Inst Municipal Invest Med, E-08003 Barcelona, Spain
:
Escola Valenciana Estudis Salut, Valencia 46017, Spain
Garcia Dos Santos, S:
Ctr Nacl Sanidad Ambiental, Inst Salud Carlos III, Madrid, Spain
:
Hosp Univ La Fe, Valencia, Spain
:
Escola Valenciana Estudis Salut, Valencia 46017, Spain
Hosp Univ La Fe, Valencia, Spain
Grimalt, J:
CSIC, Inst Invest Quim & Ambientals, Barcelona, Spain
Fernandez, M:
Univ Granada, Hosp Univ San Cecilio, Granada, Spain
:
Univ Miguel Hernandez, Dept Salud Publ, Alicante, Spain
Sala, M:
Ajuntament Sabadell, Barcelona, Spain
Tardon, A:
Univ Oviedo, Asturias, Spain
Torrent, M:
Area Salut Menorca, Islas Baleares, Spain
Ribas-Fito, N:
Inst Municipal Invest Med, E-08003 Barcelona, Spain
Sunyer, J:
Inst Municipal Invest Med, E-08003 Barcelona, Spain
:
Escola Valenciana Estudis Salut, Valencia 46017, Spain
Green Submitted, gold
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