Effectiveness of a mandibular advancement device in obstructive sleep apnea patients: a prospective clinical trial
Por:
Marco Pitarch R, Selva García M, Puertas Cuesta J, Marco Algarra J, Fernández Julian E and Fons Font A
Publicada:
1 jul 2018
Resumen:
This study aimed to determine the effectiveness of a mandibular advancement device in a sample of obstructive sleep apnea syndrome patients by the evaluation of respiratory and neurophysiologic parameters and clinical symptoms. Second, the influence of certain predictor factors related with the patient and the intraoral device, were considered in the final response with this treatment option.
Forty-one patients constituted the final sample. Outcomes were measured using polysomnography, Epworth sleepiness scale and an analogue visual snoring scale, before treatment and once the device was properly titrated.
Mean apnea-hypopnea index decreased from 22.5 +/- 16.8 to 9.1 +/- 11.6 (p > 0.05), influencing only gender and Fujita index as predictor factors. The oxygen saturation, arousal index, percentages of sleep stages and sleep efficiency significantly improved with the mandibular advancement device (MAD) placement. The snoring index improved in absolute terms in 6.1 units and the excessive daytime sleepiness was reduced from 12.2 +/- 4.7 to 8.5 +/- 3.8 (p > 0.00).
The successful treatment rate with the MAD was 65.8%. The placement and posterior regulation of the intraoral appliance efficiently reduced the apnea-hypopnea index, improved the sleep quality and the clinical symptomatology associated. Obstructive sleep apnea syndrome is a highly prevalent disease. and dentists should be aware of the benefits enhanced by this prosthetic device, considered the first treatment option by certain physicians.
Filiaciones:
Marco Pitarch R:
Unit of Prosthodontics and Occlusion, Stomatology Department, Faculty of Medicine and Dentistry, Universidad de Valencia, Calle Gasco Oliag 1, CP 46010, Valencia, Spain.
Selva García M:
Unit of Prosthodontics and Occlusion, Stomatology Department, Faculty of Medicine and Dentistry, Universidad de Valencia, Calle Gasco Oliag 1, CP 46010, Valencia, Spain
:
Sleep Unit, Neurophysiology Department, Hospital Universitario de La Ribera, Ctra. Corbera Km 1, Alzira, CP 46600, Valencia, Spain
Marco Algarra J:
Otorhinolaryngology Department, Hospital Clínico Universitario, Avenida Blasco Ibañez 17, CP 46010, Valencia, Spain
Fernández Julian E:
Otorhinolaryngology Department, Hospital Clínico Universitario, Avenida Blasco Ibañez 17, CP 46010, Valencia, Spain
Fons Font A:
Section of Prosthodontics and Occlusion, Stomatology Department, Faculty of Medicine and Dentistry, Universidad de Valencia, Calle Gasco Oliag 1, CP 46010, Valencia, Spain
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