Otoacoustic emissions in children treated with gentamicin in a secondary hospital
Por:
Sequi Canet JM, ANGELATS ROMERO, C, Sequi Sabater JM, Miralles Torres A, Boronat Garcia M and Gomez Delgado M
Publicada:
1 sep 2018
Ahead of Print:
5 mar 2018
Categoría:
Otorhinolaryngology
Resumen:
Introduction: The National Commission for the Early Detection of Hearing Loss (CODEPEH) recommends the re-evaluation of hearing in children who have suffered any potentially harmful event, such as the prescription of ototoxic antibiotics such as gentamicin. The evoked otoacoustic emissions (EOAE) are a good method for assessing the integrity of cochlear functionality.
Material and method: A prospective study is presented, including 92 children who were treated with intravenous gentamicin for septic risk/sepsis or urinary tract infection. The children underwent serial EOAE: on admission, at the end of treatment and one month later (if altered on discharge).
Results: In the end, none of the subjects were affected by the treatment.
Conclusion: Gentamicin appears to be a safe antibiotic in treatments lasting < 10 days and at the doses described. EOAE are an inexpensive, fast, non-invasive and reliable method to check for gentamicin ototoxicity. This could save in the determination of drug levels. (C) 2018 Sociedad Espanola de Otorrinolaringologia y Cirugia de Cabeza y Cuello. Published by Elsevier Espana, S.L.U. All rights reserved.
Filiaciones:
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Servicio de Pediatría, Hospital Francesc de Borja, Gandia, Valencia, España
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Servicio de Pediatría, Hospital Francesc de Borja, Gandia, Valencia, España
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Servicio de Pediatría, Hospital Francesc de Borja, Gandia, Valencia, España
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Servicio de Pediatría, Hospital Francesc de Borja, Gandia, Valencia, España
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Servicio de Laboratorio, Hospital Francesc de Borja, Gandia, Valencia, España
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Servicio de Pediatría, Hospital Francesc de Borja, Gandia, Valencia, España
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