Dairy products intake and the risk of incident cataracts surgery in an elderly Mediterranean population: results from the PREDIMED study
Por:
Camacho-Barcia L, Bulló M, García-Gavilán JF, Martínez-González MA, Corella D, Estruch R, Fitó M, Gómez-Gracia E, Arós F, Fiol M, Santos-Lozano JM, Serra-Majem L, Pintó X, Basora J, Toledo E, Muñoz MA, Zanon-Moreno V, García-Layana A and Salas-Salvadó J
Publicada:
1 mar 2019
Resumen:
ProposalThe aim of this study was to examine the association between the consumption of total and specific types of dairy products and the risk of incident cataracts in an elderly Mediterranean population at high cardiovascular risk.MethodsWe prospectively analyzed 5860 subjects from the PREvencion con DIeta MEDiterranea (PREDIMED) Study. The time to cataract surgery was calculated as the time between recruitment and the date of the surgery, last visit of the follow-up, date of death, or until the end of the study. Dairy products intake was assessed using validated food frequency questionnaires. We used Cox proportional hazard regression to assess the risk of cataract surgery according to average dietary energy-adjusted total dairy products, milk, yogurt and cheese consumption.ResultsWe documented a total of 768 new cataract events after a median of 5.6years of follow-up. Subjects in the second [hazard ratio (HR) 0.62; 95% CI 0.52, 0.74] and third tertile (HR: 0.71; 95% CI 0.60, 0.85) of skimmed yogurt intake had a significantly lower risk of cataracts after adjusting for potential confounders. No significant associations were observed for total dairy products, whole and skimmed milk, whole yogurt and cheese consumption.ConclusionThe intake of skimmed yogurt was associated with a reduced risk of cataracts in an elderly Mediterranean population with high cardiovascular risk. No significant associations were observed for other type of dairy product.Clinical Trial registrationInternational Standard Randomized Controlled Trial Number (ISRCTN): 35739639. Registration date: 5 October 2005.
Filiaciones:
Camacho-Barcia L:
Human Nutrition Unit, Biochemistry and Biotechnology Department, Faculty of Medicine and Health Sciences, University Hospital of Sant Joan de Reus, IISPV, Universitat Rovira i Virgili, St/Sant Llorenç 21, 43201, Reus, Spain
CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III, Madrid, Spain
Bulló M:
Human Nutrition Unit, Biochemistry and Biotechnology Department, Faculty of Medicine and Health Sciences, University Hospital of Sant Joan de Reus, IISPV, Universitat Rovira i Virgili, St/Sant Llorenç 21, 43201, Reus, Spain.
CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III, Madrid, Spain.
García-Gavilán JF:
Human Nutrition Unit, Biochemistry and Biotechnology Department, Faculty of Medicine and Health Sciences, University Hospital of Sant Joan de Reus, IISPV, Universitat Rovira i Virgili, St/Sant Llorenç 21, 43201, Reus, Spain
CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III, Madrid, Spain
Martínez-González MA:
CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III, Madrid, Spain
Department of Preventive Medicine and Public Health, Medical School, University of Navarra, Pamplona, Spain
:
CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III, Madrid, Spain
Department of Preventive Medicine, University of Valencia, Valencia, Spain
Estruch R:
CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III, Madrid, Spain
Department of Internal Medicine, August Pi i Sunyer Institute of Biomedical Research (IDIBAPS), Hospital Clinic, University of Barcelona, Barcelona, Spain
Fitó M:
CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III, Madrid, Spain
Cardiovascular Risk and Nutrition, Regicor Study Group, Hospital del Mar Medical Research Institute, Barcelona Biomedical Research Park, Barcelona, Spain
Gómez-Gracia E:
CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III, Madrid, Spain
Department of Preventive Medicine, University of Malaga, Malaga, Spain
Arós F:
CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III, Madrid, Spain
Department of Cardiology, University Hospital Araba, Vitoria, Spain
Fiol M:
CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III, Madrid, Spain
Department of Cardiology, University Hospital Son Dureta, Palma de Mallorca, Spain
Santos-Lozano JM:
CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III, Madrid, Spain
Department of Family Medicine, San Pablo Health Center, Sevilla, Spain
Serra-Majem L:
CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III, Madrid, Spain
Research Institute of Biomedical and Health Sciences, University of Las Palmas de Gran Canaria, Las Palmas, Spain
Pintó X:
CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III, Madrid, Spain
Lipids and Vascular Risk Unit, Internal Medicine, University Hospital of Bellvitge, Barcelona, Spain
Basora J:
Human Nutrition Unit, Biochemistry and Biotechnology Department, Faculty of Medicine and Health Sciences, University Hospital of Sant Joan de Reus, IISPV, Universitat Rovira i Virgili, St/Sant Llorenç 21, 43201, Reus, Spain
Toledo E:
CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III, Madrid, Spain
Emergency Department, Navarra's Hospital Complex, National Health Service-Osasunbidea, Pamplona, Spain
Muñoz MA:
CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III, Madrid, Spain
Primary Health Care Division, Institut Català de la Salut and Idiap-Jordi Gol, Barcelona, Spain
:
Department of Preventive Medicine, University of Valencia, Valencia, Spain
Ophthalmic Research Unit "Santiago Grisolía" Valencia, Valencia, Spain
Red Temática de Patología Ocular OFTARED, ISCIII, Madrid, Spain
García-Layana A:
CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III, Madrid, Spain
Department of Ophthalmology, University of Navarra, Pamplona, Spain
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