Methadone, Pierre Robin sequence and other congenital anomalies: case-control study.
Por:
Cleary B, Loane M, Addor MC, Barisic I, de Walle HEK, Matias Dias C, Gatt M, Klungsoyr K, McDonnell B, Neville A, Pierini A, Rissmann A, Tucker DF, Zurriaga, O and Dolk H
Ahead of Print:
22 jun 2019
Resumen:
Methadone is a vital treatment for women with opioid use disorder in pregnancy. Previous reports suggested an association between methadone exposure and Pierre Robin sequence (PRS), a rare craniofacial anomaly. We assessed the association between gestational methadone exposure and PRS.
Filiaciones:
Cleary B:
Pharmacy Department, Rotunda Hospital, Dublin, Ireland
School of Pharmacy, Royal College of Surgeons in Ireland, Dublin, Ireland
Loane M:
Centre for Maternal, Fetal and Infant Research, INHR, Ulster University, Newtowanbbey, UK
Addor MC:
Division Autonome de Genetique Medicale, Registre Vaudois des Malformations, Vaud, Switzerland
Barisic I:
Children's Hospital Zagreb, School of Medicine, University of Zagreb, Zagreb, Croatia
de Walle HEK:
Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Matias Dias C:
Centro de Estudos e registo de A C, Lisbon, Portugal
Gatt M:
Department of Health Information, Malta Congenital Anomalies Registry, G'mangia, Malta
Klungsoyr K:
Medical Birth Register of Norway, Nasjonalt folkehelseinstitutt, Oslo, Norway
McDonnell B:
Health Service Executive, Dublin, Ireland
Neville A:
Azienda Ospedaliero - Universitaria di Ferrara, Registro IMER, Ferrara, Italy
Pierini A:
Istituto di Fisiologia Clinica CNR, Pisa, Italy
Rissmann A:
Malformation Monitoring Centre Saxony-Anhalt, Medical Faculty Otto-von-Guericke University, Magdeburg, Germany
Tucker DF:
Congenital Anomaly Register and Information Service for Wales, Public Health Wales, Swansea, UK
:
Centro Superior de Investigación en Salud Pública, Valencia, Spain. Área de Desigualdades en Salud. Fisabio
Direccion General de Investigación y Salud Pública, Valencia, Spain
Dolk H:
University of Ulster, Jordanstown, UK
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