Optimization of Resolving Power, Fragmentation, and Mass Calibration in an Orbitrap Spectrometer for Analysis of 24 Pesticide Metabolites in Urine
Por:
Dualde, P, Coscolla, C, Pastor, A and Yusa, V
Publicada:
1 ene 2019
Ahead of Print:
17 abr 2019
Categoría:
Analytical chemistry
Resumen:
Mass spectrometer parameters such as Resolving Power, type of fragmentation, and mass calibration mode were optimized in the analysis of 24 pesticide metabolites in human urine using Ultra-High Pressure Liquid Chromatography coupled to Orbitrap High-Resolution Mass Spectrometer (UHPLC-HRMS). The best results were achieved with a Resolving Power of 25,000 FWHM and by applying Collision Induced Dissociation fragmentation mode (40 eV).
Filiaciones:
:
Área de Seguridad Alimentaria. Foundation for the Promotion of Health and Biomedical Research in the Valencian Region, FISABIO-Public Health, 21 Avenida Catalunya, 46020 Valencia, Spain
Analytical Chemistry Department, University of Valencia, Edifici Jeroni Muñoz, Dr. Moliner 50, 46100 Burjassot, Spain
:
Área de Seguridad Alimentaria. Foundation for the Promotion of Health and Biomedical Research in the Valencian Region, FISABIO-Public Health, 21 Avenida Catalunya, 46020 Valencia, Spain
Public Health Laboratory of Valencia, 21 Avenida Catalunya, 46020 Valencia, Spain
Pastor, A:
Analytical Chemistry Department, University of Valencia, Edifici Jeroni Muñoz, Dr. Moliner 50, 46100 Burjassot, Spain
:
Área de Seguridad Alimentaria. Foundation for the Promotion of Health and Biomedical Research in the Valencian Region, FISABIO-Public Health, 21 Avenida Catalunya, 46020 Valencia, Spain
Analytical Chemistry Department, University of Valencia, Edifici Jeroni Muñoz, Dr. Moliner 50, 46100 Burjassot, Spain
Public Health Laboratory of Valencia, 21 Avenida Catalunya, 46020 Valencia, Spain
Green Published, Green Submitted, gold
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