Multiple myeloma associated with a secondary amyloidosis. Report of one case
Por:
Rodríguez-Lagos FA, Sorlí JV, Calviño-Naveira MC and Capell NE
Publicada:
1 nov 2018
Categoría:
Medicine (miscellaneous)
Resumen:
Multiple Myeloma is a myeloproliferative disorder of plasma cells, which may be complicated with secondary amyloidosis. We report a 48 year old woman consulting to primary care for weight loss and malaise. An initial laboratory study revealed a hypogammaglobulinemia with a monoclonal component and lambda light chains. These results motivated her derivation to hematology: her serum calcium was 11.8 mg/dl, immunofluorescence showed a monoclonal component of lambda chains and urine Bence-Jones protein was positive. A bone marrow biopsy confirmed plasma cell infiltration. A Congo-red stain of a rectal biopsy was positive. The patient was treated with thalidomide, bortezomid and dexamethasone.
Filiaciones:
:
Servicio de Análisis Clínicos, Hospital Universitario Dr. Peset, Valencia, España
:
aff2, España
Calviño-Naveira MC:
aff2, España
:
Servicio de Análisis Clínicos, Hospital Universitario Dr. Peset, Valencia, España
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