European evidence-based guidelines on pancreatic cystic neoplasms
Por:
Del Chiaro, M, Besselink, M, Scholten, L, Bruno, M, Cahen, D, Gress, T, van Hooft, J, Lerch, M, Mayerle, J, Hackert, T, Satoi, S, Zerbi, A, Cunningham, D, De Angelis, C, Giovanni, M, De madaria E, Hegyi, P, Rosendahl, J, Friess, H, Manfredi, R, Levy, P, Real, F, Sauvanet, A, Abu Hilal, M, Marchegiani, G, Esposito, I, Ghaneh, P, Engelbrecht, M, Fockens, P, van Huijgevoort, N, Wolfgang, C, Bassi, C, Gubergrits, N, Verbeke, C, Kloppel, G, Scarpa, A, Zamboni, G, Lennon, A, Sund, M, Kartalis, N, Grenacher, L, Falconi, M, Arnelo, U, Kopchak, K, Oppong, K, McKay, C, Hauge, T, Conlon, K, Adham, M, Ceyhan, G, Salvia, R, Dervenis, C, Allen, P, Paye, F, Bartsch, D, Lohr, M, Mutignani, M, Laukkarinen, J, Schulick, R, Valente, R, Seufferlein, T, Capurso, G, Siriwardena, A, Neoptolemos, J, Pukitis, A, Segersvard, R, Aghdassi, A, Andrianello, S, Bossuyt, P, Bulow, R, Cardenas-Jaen, K, Cortegoso, P, Fontana, M, Haeberle, L, Heckler, M, Litvin, A, Mann, K, Michalski, C, Michl, P, Nappo, G, Perri, G, Persson, S, Scheufele, F, Sclafani, F, Schmidt, M, Venezia, L, Volker, F, Vullierm, M, Wusten, L and European Study Grp Cystic Tum
Publicada:
1 may 2018
Categoría:
Gastroenterology
Resumen:
Evidence-based guidelines on the management of pancreatic cystic
neoplasms (PCN) are lacking. This guideline is a joint initiative of the
European Study Group on Cystic Tumours of the Pancreas, United European
Gastroenterology, European Pancreatic Club, European-African
Hepato-Pancreato-Biliary Association, European Digestive Surgery, and
the European Society of Gastrointestinal Endoscopy. It replaces the 2013
European consensus statement guidelines on PCN. European and
non-European experts performed systematic reviews and used GRADE
methodology to answer relevant clinical questions on nine topics
(biomarkers, radiology, endoscopy, intraductal papillary mucinous
neoplasm (IPMN), mucinous cystic neoplasm (MCN), serous cystic neoplasm,
rare cysts, (neo)adjuvant treatment, and pathology). Recommendations
include conservative management, relative and absolute indications for
surgery. A conservative approach is recommended for asymptomatic MCN and
IPMN measuring < 40 mm without an enhancing nodule. Relative indications
for surgery in IPMN include a main pancreatic duct (MPD) diameter
between 5 and 9.9 mm or a cyst diameter >= 40 mm. Absolute indications
for surgery in IPMN, due to the high-risk of malignant transformation,
include jaundice, an enhancing mural nodule > 5 mm, and MPD diameter >
10 mm. Lifelong follow-up of IPMN is recommended in patients who are fit
for surgery. The European evidence-based guidelines on PCN aim to
improve the diagnosis and management of PCN.
Filiaciones:
Del Chiaro, M:
Karolinska Inst, Karolinska Univ Hosp, Div Surg, Pancreat Surg Unit, Stockholm, Sweden
Besselink, M:
Acad Med Ctr, Canc Ctr Amsterdam, Dept Surg, Amsterdam, Netherlands
Scholten, L:
Acad Med Ctr, Canc Ctr Amsterdam, Dept Surg, Amsterdam, Netherlands
Bruno, M:
Erasmus Univ, Dept Gastroenterol & Hepatol, Med Ctr, Rotterdam, Netherlands
Cahen, D:
Erasmus Univ, Dept Gastroenterol & Hepatol, Med Ctr, Rotterdam, Netherlands
Gress, T:
Philipps Univ Marburg, Dept Gastroenterol, Marburg, Germany
Univ Hosp Marburg, Dept Gastroenterol Endocrinol Metab & Infectiol, Marburg, Germany
van Hooft, J:
Acad Med Ctr, Dept Gastroenterol, Amsterdam Gastroenterol & Metab, Amsterdam, Netherlands
Lerch, M:
Univ Med Greifswald, Dept Med A, Greifswald, Germany
Mayerle, J:
Univ Med Greifswald, Dept Gastroenterol Endocrinol & Nutr, Greifswald, Germany
Hackert, T:
Heidelberg Univ, Dept Surg, Heidelberg, Germany
Zerbi, A:
Humanitas Univ, Pancreat Surg, Rozzano, MI, Italy
Cunningham, D:
Royal Marsden, Dept Internal Med, London, England
De Angelis, C:
Citta Saluta & Sci, Dept Gastroenterol, Digest Endoscopy Serv, Turin, Italy
De madaria E:
Hosp Gen Univ Alicante, Alicante Inst Hlth & Biomed Res, Dept Gastroenterol, ISABIAL FISABIO Fdn, Alicante, Spain
Hegyi, P:
Univ Szeged, Momentum Translat Gastroenterol Res Grp, Hungarian Acad Sci, Szeged, Hungary
Univ Pecs, Inst Translat Med, Pecs, Hungary
Univ Pecs, Dept Med 1, Pecs, Hungary
Rosendahl, J:
Martin Luther Univ Halle Wittenberg, Dept Internal Med, D-06120 Halle, Saale, Germany
Friess, H:
Tech Univ Munich, Dept Surg, Klinikum Rechts Isar, Ismaninger Str 22, D-81675 Munich, Germany
Manfredi, R:
Univ Rome, Dept Radiol, Fdn Policlin Gemelli, 8 Lgo A Gemelli, I-00168 Rome, Italy
Levy, P:
Univ Paris 07, Hosp Beaujon, Dept Pancreatol Gastroenterol, Clichy, France
Real, F:
Spanish Natl Canc Res Ctr CNIO, Epithelial Carcinogenesis Grp, Canc Cell Biol Programme, Madrid, Spain
Univ Pompeu Fabra, Dept Ciencies Expt & Salut, Barcelona, Spain
Sauvanet, A:
Hop Beaujon, AP HP, Dept HPB Surg, F-92110 Clichy, France
Abu Hilal, M:
Univ Hosp Southampton NHS Fdn Trust, Dept HPB Surg, Southampton, England
Marchegiani, G:
Verona Univ Hosp, Pancreas Inst, Dept Surg, Verona, Italy
Esposito, I:
Heinrich Heine Univ, Inst Pathol, Dusseldorf, Germany
Ghaneh, P:
Univ Liverpool, Dept Mol & Clin Canc Med, Liverpool, Merseyside, England
Engelbrecht, M:
Acad Med Ctr Amsterdam, Dept Radiol, Amsterdam, Netherlands
Fockens, P:
Acad Med Ctr, Dept Gastroenterol, Amsterdam Gastroenterol & Metab, Amsterdam, Netherlands
van Huijgevoort, N:
Acad Med Ctr, Dept Gastroenterol, Amsterdam Gastroenterol & Metab, Amsterdam, Netherlands
Wolfgang, C:
Johns Hopkins Univ Hosp, Dept Surg, Baltimore, MD 21287 USA
Bassi, C:
Univ Verona, Hosp GB Rossi, Surg & Gastroenterol Dept, Verona, Italy
Gubergrits, N:
Donetsk Natl Med Univ, Dept Internal Med, Donetsk, Ukraine
Verbeke, C:
Univ Oslo, Inst Clin Med, Dept Pathol, Oslo, Norway
Kloppel, G:
Univ Kiel, Dept Pathol, Michaelisstr 11, D-24005 Kiel, Germany
Scarpa, A:
Univ & Hosp Trust Verona, Dept Pathol, Verona, Italy
Zamboni, G:
Univ & Hosp Trust Verona, Dept Pathol, Verona, Italy
Lennon, A:
Johns Hopkins Univ Hosp, Dept Gastroenterol, Baltimore, MD 21287 USA
Sund, M:
Univ Umea, Dept Surg & Perioperat Sci, Umea, Sweden
Kartalis, N:
Karolinska Inst, Div Med Imaging & Technol, Dept Clin Sci Intervent & Technol CLINTEC, Stockholm, Sweden
Karolinska Univ Hosp, Dept Radiol, Stockholm, Sweden
Grenacher, L:
Heidelberg Univ, Dept Radiol, Heidelberg, Germany
Arnelo, U:
Karolinska Inst, Karolinska Univ Hosp, Div Surg, Pancreat Surg Unit, Stockholm, Sweden
Kopchak, K:
Natl Canc Inst, Dept Surg, Kiev, Ukraine
Oppong, K:
Newcastle Upon Tyne Hosp, Dept Gastroenterol, Newcastle Upon Tyne, Tyne & Wear, England
McKay, C:
Glasgow Royal Infirm, Dept Surg, Glasgow, Lanark, Scotland
Hauge, T:
Oslo Univ Hosp, Dept Gastroenterol, Oslo, Norway
Conlon, K:
Trinity Coll Dublin, Tallaght Hosp, Dept Surg, Dublin, Ireland
Adham, M:
Ctr Hosp Univ Lyon, Dept Surg, Lyon, France
Ceyhan, G:
Tech Univ Munich, Dept Surg, Klinikum Rechts Isar, Munich, Germany
Salvia, R:
Univ Verona Hosp Trust, Dept Gen & Pancreat Surg, Pancreas Inst, Verona, Italy
Dervenis, C:
Konstantopoule Gen Hosp Athens, Dept Surg, Athens, Greece
Allen, P:
Mem Sloan Kettering Canc Ctr, Dept Surg, 1275 York Ave, New York, NY 10021 USA
Paye, F:
Hop St Antoine, AP HP, Dept Digest Surg, Paris, France
Bartsch, D:
Philipps Univ Marburg, Dept Visceral Thorac & Vasc Surg, Marburg, Germany
Lohr, M:
Karolinska Inst, Karolinska Univ Hosp, Div Surg, Pancreat Surg Unit, Stockholm, Sweden
Mutignani, M:
Catholic Univ, Dept Surg, Rome, Italy
Laukkarinen, J:
Tampere Univ Hosp, Dept Gastroenterol & Alimentary Tract Surg, Tampere, Finland
Schulick, R:
Univ Colorado Hosp, Dept Surg, Aurora, CO USA
Valente, R:
Karolinska Univ Hosp, Ctr Digest Dis, Stockholm, Sweden
Seufferlein, T:
Martin Luther Univ Halle Wittenberg, Dept Internal Med 4, Halle, Saale, Germany
Capurso, G:
Sapienza Univ Rome, S Andrea Hosp, Fac Med & Psychol, Digest & Liver Dis Unit, Rome, Italy
Siriwardena, A:
Cent Manchester Univ Hosp, Dept Surg, Manchester, Lancs, England
Neoptolemos, J:
Univ Athens, Gen Surg, Athens, Greece
Pukitis, A:
Univ Latvia, Dept Internal Med, Riga, Latvia
Segersvard, R:
Karolinska Inst, Karolinska Univ Hosp, Div Surg, Pancreat Surg Unit, Stockholm, Sweden
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