Oleic acid chlorohydrin, a new early biomarker for the prediction of acute pancreatitis severity in humans.
Por:
De madaria E, Molero X, Bonjoch, L, Casas, J, Cardenas K, Montenegro, A and Closa, D
Publicada:
9 ene 2018
Categoría:
Critical care and intensive care medicine
Resumen:
The early prediction of the severity of acute pancreatitis still represents a challenge for clinicians. Experimental studies have revealed the generation of specific halogenated lipids, in particular oleic acid chlorohydrin, in the early stages of acute pancreatitis. We hypothesized that the levels of circulating oleic acid chlorohydrin might be a useful early prognostic biomarker in acute pancreatitis in humans.
Filiaciones:
De madaria E:
Pancreatic Unit, Department of Gastroenterology, Hospital General Universitario de Alicante, Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL - Fundación FISABIO), Alicante, Spain
Hosp Gen Univ Alicante, Pancreat Unit, Dept Gastroenterol,Fdn FISABIO, Inst Invest Sanitaria & Biomed Alicante ISABIAL, Alicante, Spain
Molero X:
Univ Autonoma Barcelona, CIBEREHD, Inst Recerca VHIR, Hosp Univ Vall dHebron,Exocrine Pancreat Dis Res, Barcelona, Spain
Bonjoch, L:
IDIBAPS, IIBB CSIC, Dept Expt Pathol, C Rossello 161,7, Barcelona 08036, Spain
Casas, J:
IQAC CSIC, Dept Biomedicinal Chem, RUBAM, Barcelona, Spain
Cardenas K:
Hosp Gen Univ Alicante, Pancreat Unit, Dept Gastroenterol,Fdn FISABIO, Inst Invest Sanitaria & Biomed Alicante ISABIAL, Alicante, Spain
Montenegro, A:
Univ Autonoma Barcelona, CIBEREHD, Inst Recerca VHIR, Hosp Univ Vall dHebron,Exocrine Pancreat Dis Res, Barcelona, Spain
Closa, D:
IDIBAPS, IIBB CSIC, Dept Expt Pathol, C Rossello 161,7, Barcelona 08036, Spain
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