Redefining the therapeutic objective in psoriatic patients candidates for biological therapy
Por:
Carretero, G, Puig, L, Carrascosa, J, Ferrandiz, L, Ruiz-Villaverde, R, de la Cueva, P, Belinchon I, Vilarrasa, E, del Rio, R, Sanchez-Carazo, J, Lopez-Ferrer, A, Peral, F, Armesto, S, Eiris, N, Mitxelena, J, Vilar-Alejo, J, Martin, M and Soria, C
Publicada:
1 ene 2018
Categoría:
Dermatology
Resumen:
The advances in psoriasis management currently allow achieving a good
control of the disease. In particular, with the latest developed
molecules, available evidence suggests that it is possible to pose an
ambitious therapeutic goal, such as a Dermatology Life Quality Index
0/1, a Physician Global Assessment 0/1, or a Psoriasis Area and Severity
Index 90/100 response. However, patients often fail to achieve the
complete clearance of their cutaneous lesions or the improvement of
disease factors that impair their quality of life. To optimize the
treatment of psoriasis, it is not enough to define precisely the
therapeutic objective, but also to adapt the therapeutic strategy to
make the necessary modifications in case of not achieving it at the time
point (at the end of the induction phase, or every 3-6months) to be
agreed with the patient (the so-called treat-to-target approach). In the
present report, based on the Delphi methodology, 11 dermatologists from
the Spanish Psoriasis Group addressed key issues that could be involved
in the achievement and maintenance of the therapeutic goals of patients
with moderate to severe psoriasis. The document provides 27 consensus
statements intended to support clinical decision-making by healthcare
professionals for patients who might be candidates to receive biologic
therapy.
Filiaciones:
Carretero, G:
Hosp Univ Gran Canaria Doctor Negrin, Las Palmas Gran Canaria, Spain
Puig, L:
Univ Autonoma Barcelona, Hosp Santa Creu & St Pau, Barcelona, Spain
Carrascosa, J:
Univ Autonoma Barcelona, Hosp Univ Germans Trias & Pujol, Badalona, Spain
Ferrandiz, L:
Hosp Univ Virgen Macarena, Seville, Spain
Ruiz-Villaverde, R:
Complejo Hosp Granada, Granada, Spain
de la Cueva, P:
Hosp Univ Infanta Leonor, Madrid, Spain
Belinchon I:
Hosp Gen Univ Alicante ISABIAL, Alicante, Spain
Vilarrasa, E:
Univ Autonoma Barcelona, Hosp Santa Creu & St Pau, Barcelona, Spain
del Rio, R:
Fundacio Hosp Esperit St, Santa Coloma De Gramenet, Spain
Sanchez-Carazo, J:
Consorcio Hosp Gen Univ Valencia, Valencia, Spain
Lopez-Ferrer, A:
Univ Autonoma Barcelona, Hosp Santa Creu & St Pau, Barcelona, Spain
Peral, F:
Hosp Univ Infanta Cristina Badajoz, Badajoz, Spain
Armesto, S:
Hosp Univ Marques de Valdecilla, Santander, Spain
Eiris, N:
Complejo Asistencial Univ Leon, Leon, Spain
Mitxelena, J:
Complejo Hosp Navarra, Navarra, Spain
Vilar-Alejo, J:
Hosp Univ Gran Canaria Doctor Negrin, Las Palmas Gran Canaria, Spain
Martin, M:
Hosp Clin Univ Lozano Blesa, Zaragoza, Spain
Soria, C:
Hosp Gen Univ Reina Sofia, Murcia, Spain
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