Dietary exposure and risk assessment of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and dioxin-like polychlorinated biphenyls of the population in the Region of Valencia (Spain)
Por:
Quijano L, Marin S, Millan E, Yusa V, Font G and Pardo O
Publicada:
1 ene 2018
Ahead of Print:
8 dic 2017
Resumen:
Dietary exposure of the Valencia Region population to polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and PCBs was assessed in the Region of Valencia in 2010-2011. A total of 7700 food samples were collected. Occurrence data were combined with consumption data to estimate dietary exposure in adults (>15years of age) and young people (6-15years of age). The estimated intake was calculated by a probabilistic approach. Average intake levels (upper-bound scenario) were 1.58 and 2.76 pg toxic equivalent (TEQ) kg(-1) body weight (bw) day(-1) for adults and young people, respectively. These average intakes are within range of the tolerable daily intake of 1-4 pg WHO-TEQ kg(-1) bw day(-1) recommended by WHO, and slightly above the tolerable weekly intake (TWI) of 14 pg TEQ kg(-1) bw week(-1) and the Provisional tolerable monthly intake of 70 pg TEQ kg(-1) bw month(-1) set by the Scientific Committee on Food and the Joint FAO/WHO Expert Committee on Food, respectively. These results show that the contamination levels in food and therefore the exposure of the general population to PCDD/Fs and PCBs have declined in this region and therefore show the efficiency of the European risk-management measures. In terms of risk characterisation, the results showed that, under the upper-bound scenario, 22% of the adult and 58% of the young people population could exceed the TWI.
Filiaciones:
:
a Preventive Medicine and Public Health, Food Sciences, Toxicology and Forensic Medicine Department , University of Valencia , Av. Vicent Andres Estelles s/n, 46100 Burjassot, Valencia , Spain
:
b Food Safety Research Area , Center for Public Health Research (CSISP) , FISABIO. Av. Catalunya, 21, 46020 , Valencia , Spain
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c Public Health Laboratory of Valencia , 21 Avenida Catalunya, 46020 Valencia , Spain
:
b Food Safety Research Area , Center for Public Health Research (CSISP) , FISABIO. Av. Catalunya, 21, 46020 , Valencia , Spain
c Public Health Laboratory of Valencia , 21 Avenida Catalunya, 46020 Valencia , Spain
d Analytical Chemistry Department. University of Valencia , Av. Vicent Andres Estelles s/n, 46100 Burjassot, Valencia , Spain
Font G:
a Preventive Medicine and Public Health, Food Sciences, Toxicology and Forensic Medicine Department , University of Valencia , Av. Vicent Andres Estelles s/n, 46100 Burjassot, Valencia , Spain
:
b Food Safety Research Area , Center for Public Health Research (CSISP) , FISABIO. Av. Catalunya, 21, 46020 , Valencia , Spain
c Public Health Laboratory of Valencia , 21 Avenida Catalunya, 46020 Valencia , Spain
d Analytical Chemistry Department. University of Valencia , Av. Vicent Andres Estelles s/n, 46100 Burjassot, Valencia , Spain
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