Fine-tuning of antithrombotic therapy in patients with non-valvular atrial fibrillation. The AFINVA register
Por:
Dubois Marques D, Mora Llabata V, Pacheco Arroyo J, Gasull Insertis S, Vicente Canizares M and Roldan Torres I
Publicada:
1 jun 2018
Ahead of Print:
31 ago 2017
Resumen:
Objective: To determine whether antithrombotic treatment (ATT) in patients with non-valvular atrial fibrillation in a health area complies with the recommendations of current clinical guidelines.
Design: Prospective observational study.
Location: Primary Health Care Centres and Cardiology Department of a Health Department of the Valencian Community, Spain.
Participants: A total of 505 patients with nonvalvular atrial fibrillation were included in the study.
Main measurements: ATT was deemed to be inappropriate in patients with a CHA(2)DS(2)-VASc score >= 1 and who were not under oral anticoagulation, in patients treated with antivitamin K drugs, and poor control of oral anticoagulation, or with antiplatelet therapy inappropriately associated with anticoagulation, and in patients on ATT with a CHA(2)DS(2)-VASc score = 0.
Results: The median age was 77.4 +/- 10 years. The ATT was considered inadequate in 58% of cases. Factors independently associated with inadequate ATT were age (OR: 1.02 [1-1.04]; P=.029), hypothyroidism (OR: 1.98 [1.14-3.43]; P=.015), ischaemic heart disease (OR: 1.3 [1.15-2.59]; P=.008) and paroxysmal non -valvular AF (OR: 2.11 [1.41-3.17]; P <.0001).
Conclusions: These data underline the high prevalence of inadequate ATT in daily practice, as well its different causes. (C) 2017 Elsevier Espana, S.L.U.
Filiaciones:
:
Servicio de Cardiologia, Hospital Universitario Dr Peset, Valencia, Espana
:
Servicio de Cardiologia, Hospital Universitario Dr Peset, Valencia, Espana
:
Centro de Salud Fuente de San Luis, Valencia, Espana
:
Centro de Salud Vicente Clavet, Valencia, Espana
:
Centro de Salud Ingeniero Joaquin Benlloch, Valencia, Espana
:
Servicio de Cardiologia, Hospital Universitario Dr Peset, Valencia, Espana
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