Norfloxacin is more effective than Rifaximin in avoiding bacterial translocation in an animal model of cirrhosis.
Por:
Gómez I, Gimenez P, Garcia I, Zapater P, Frances R, Gonzalez J, Manichanh C, Ramos J, Bellot P, Guarner F and Such J
Publicada:
1 feb 2018
Ahead of Print:
18 ago 2017
Categoría:
Hepatology
Resumen:
Norfloxacin administration is useful in preventing bacterial infections in cirrhosis but associated to the generation of resistant species. Rifaximin is known to reach high concentrations in the intestinal lumen without generating relevant resistance in the intestinal flora. Our aim was to compare the effect of Norfloxacin and Rifaximin on intestinal flora composition, bacterial translocation and survival in cirrhotic rats.
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