Diabetes Does Not Increase the Risk of Hospitalization Due to COVID-19 in Patients Aged 50 Years or Older in Primary Care-APHOSDIAB-COVID-19 Multicenter Study
Por:
Orozco D, Merino-Torres, J, Perez, A, Cebrian-Cuenca, A, Parraga-Martinez, I, Avila-Lachica, L, Rojo-Martinez, G, Pomares-Gomez, F, Alvarez-Guisasola, F, Sanchez-Molla, M, Gutierrez, F, Ortega, F, Mata-Cases, M, Carretero-Anibarro, E, Vilaseca, J and Quesada, J
Publicada:
1 abr 2022
Categoría:
Medicine (miscellaneous)
Resumen:
The purpose of this study was to identify clinical, analytical, and sociodemographic variables associated with the need for hospital admission in people over 50 years infected with SARS-CoV-2 and to assess whether diabetes mellitus conditions the risk of hospitalization. A multicenter case-control study analyzing electronic medical records in patients with COVID-19 from 1 March 2020 to 30 April 2021 was conducted. We included 790 patients: 295 cases admitted to the hospital and 495 controls. Under half (n = 386, 48.8%) were women, and 8.5% were active smokers. The main comorbidities were hypertension (50.5%), dyslipidemia, obesity, and diabetes (37.5%). Multivariable logistic regression showed that hospital admission was associated with age above 65 years (OR from 2.45 to 3.89, ascending with age group); male sex (OR 2.15, 95% CI 1.47-3.15), fever (OR 4.31, 95% CI 2.87-6.47), cough (OR 1.89, 95% CI 1.28-2.80), asthenia/malaise (OR 2.04, 95% CI 1.38-3.03), dyspnea (4.69, 95% CI 3.00-7.33), confusion (OR 8.87, 95% CI 1.68-46.78), and a history of hypertension (OR 1.61, 95% CI 1.08-2.41) or immunosuppression (OR 4.97, 95% CI 1.45-17.09). Diabetes was not associated with increased risk of hospital admission (OR 1.18, 95% CI 0.80-1.72; p = 0.38). Diabetes did not increase the risk of hospital admission in people over 50 years old, but advanced age, male sex, fever, cough, asthenia, dyspnea/confusion, and hypertension or immunosuppression did.
Filiaciones:
Orozco D:
Consejeria Sanidad Univesal & Salud Publ, Hlth Ctr Cabo Huertas, Alicante 03540, Spain
Spanish Diabet Soc, Madrid 28002, Spain
Univ Miguel Hernandez, Clin Medice Dept, Alicante 03550, Spain
Merino-Torres, J:
Univ Valencia, Hosp Univ & Politecn La Fe, Endocrinol & Nutr Serv, Valencia 46026, Spain
Perez, A:
Spanish Diabet Soc, Madrid 28002, Spain
Autonoums Univ Barcelona, Med Dept, Barcelona 08193, Spain
Biomed Res Network Diabet & Associated Metab Diso, Madrid 20029, Spain
Serv Catalan Salud, Hosp Santa Creu & St Pau, Barcelona 08041, Spain
:
Primary Care & Prediabet Grp Spanish Diabet Soc, Cartagena 30201, Spain
Serv Murciano Salud, Hlth Ctr Cartagena Casco, Cartagena 30201, Spain
Biomed Res Inst Murcia IMIB, Primary Care Res Grp, Murcia 30120, Spain
Parraga-Martinez, I:
Spanish Soc Family & Community Med SemFyC, Madrid 28004, Spain
Serv Salud Castilla Mancha, Hlth Ctr Zone 8, Albacete 02006, Spain
Avila-Lachica, L:
Grp DM SemFyC, GAPP SED, Madrid 28004, Spain
UGC Velez Norte, Consultorio Almachar, Malaga 29718, Spain
Rojo-Martinez, G:
Spanish Diabet Soc, Madrid 28002, Spain
Biomed Res Network Diabet & Associated Metab Diso, Madrid 20029, Spain
Malaga Reg Univ Hosp, Endocrinol & Nutr Clin Management Unit, Biomed Res Inst IBIMA, Malaga 29010, Spain
:
Univ Hosp San Juan Alicante, Diabet Mellitus Plan Valencian Community, Alicante 03550, Spain
Alvarez-Guisasola, F:
Spanish Soc Family & Community Med SemFyC, Madrid 28004, Spain
Consejeria Salud Castilla Leon, Hlth Ctr Ribera Orbigo, Leon 24280, Spain
:
Elche Gen Univ Hosp, Elche 03203, Spain
:
Univ Miguel Hernandez, Clin Medice Dept, Alicante 03550, Spain
Elche Gen Univ Hosp, Internal Med, Elche 03203, Spain
CIBER Infect Dis, Madrid 28029, Spain
Ortega, F:
Conserjeria Salud Castilla & Leon, Hlth Ctr Campos Lampreana, Zamora 49137, Spain
Mata-Cases, M:
Serv Catalan Salud, Primary Care Ctr La Mina, Barcelona 08930, Spain
CIBERDEM, Res Support Unit, Jordi Gol Univ Inst Primary Healthcare Res, Grp DAP Cat, Barcelona 08036, Spain
Carretero-Anibarro, E:
Serv Andauz Salud, Hlth Ctr Jose Gallego Arroba, Cordoba 14500, Spain
Vilaseca, J:
Univ Barcelona, Med Dept, Barcelona 08007, Spain
:
Univ Miguel Hernandez, Clin Medice Dept, Alicante 03550, Spain
Green Published, gold
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