Dermoscopic Rosettes as a Clue for Pigmented Incipient Melanoma
Por:
Gonzalez-Alvareza, T, Armengot-Carbo, M, Barreiro, A, Alarcon, L, Carrera, C, Garcia, A, Malvehy, J and Puig, S
Publicada:
1 ene 2014
Categoría:
Dermatology
Resumen:
The rosette structure is a dermoscopic sign visible under polarized light, characterized by 4 white points arranged as a 4-leaf clover. It has been mainly described in facial sun-damaged skin and actinic keratosis, although it has also been found in squamous and basal cell carcinomas, and in 2 cases of hypomelanotic melanomas. We describe 2 different cases of pigmented incipient melanomas with the presence of multiple rosettes and shiny white structures on dermoscopy. In the reflectance confocal microscope they exhibit a disarranged epidermal architecture with atypical and dendritic cells. Histological examination showed focal hyperkeratosis and a normal corneal layer presented alternatively. To our knowledge this is the first description of rosette structures in pigmented melanomas. Based on a proper dermoscopic-confocal-histopathological correlation, we hypothesize that rosettes could correspond to optic phenomena due to changes in the superficial epidermal reaction and in the acrosyringia. (C) 2013 S. Karger AG, Basel
Filiaciones:
Gonzalez-Alvareza, T:
Univ Barcelona, Hosp Clin, Dept Dermatol, E-08007 Barcelona, Spain
:
Univ Barcelona, Hosp Clin, Dept Dermatol, E-08007 Barcelona, Spain
Hosp Arnau Vilanova, Dept Dermatol, Valencia, Spain
Barreiro, A:
Univ Barcelona, Hosp Clin, Dept Dermatol, E-08007 Barcelona, Spain
Alarcon, L:
Univ Barcelona, Hosp Clin, Dept Dermatol, E-08007 Barcelona, Spain
Carrera, C:
Univ Barcelona, Hosp Clin, Dept Dermatol, E-08007 Barcelona, Spain
ISCIII, Ctr Invest Biomed Enfermedades Raras, Barcelona, Spain
Garcia, A:
Univ Barcelona, Hosp Clin, Pathol Serv, Melanoma Unit, E-08007 Barcelona, Spain
Univ Barcelona, Inst Invest Biomed August Pi & Sunyer, E-08007 Barcelona, Spain
Malvehy, J:
Univ Barcelona, Hosp Clin, Dept Dermatol, E-08007 Barcelona, Spain
ISCIII, Ctr Invest Biomed Enfermedades Raras, Barcelona, Spain
Puig, S:
Univ Barcelona, Hosp Clin, Dept Dermatol, E-08007 Barcelona, Spain
ISCIII, Ctr Invest Biomed Enfermedades Raras, Barcelona, Spain
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