Evolution of the emotional impact in patients with early inflammatory bowel disease during and after Covid-19 lockdown
Por:
Sempere, L, Bernabeu, P, Cameo, J, Gutierrez, A, Laveda, R, Garcia, M, Aguas, M, Zapater, P, Jover, R, Ruiz-Cantero, M and van-der Hofstadt, C
Publicada:
1 feb 2022
Ahead of Print:
1 feb 2022
Resumen:
Background: Patients with inflammatory bowel disease (IBD) are vulnerable to some psychological disorders. Here we describe the psychological impact of a COVID-19 pandemic lockdown in patients with IBD.
Methods: This multicenter prospective cohort study included 145 patients recently diagnosed with IBD. Data on clinical and demographic characteristics, anxiety and depression scales, and IBD activity were collected in two telephone surveys, during and after the first COVID-19 lockdown in Spain. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated.
Results: During lockdown, 33.1% and 24.1% scored high on the anxiety and depression scales, respectively. Independent factors related to anxiety (all values ORs; 95% CIs) during lockdown were female sex (2; 1.2-5.4) and IBD activity (4.3; 1.8-10.4). Factors related to depression were comorbidity (3.3; 1.1-9.8), IBD activity (6; 1.9-18.1), use of biologics (2.9; 1.1-7.6), and living alone or with one person (3.1; 1.2-8.2). After lockdown, anxiety and depression symptoms showed significant improvement, with 24.8% and 15.2% having high scores for anxiety and depression, respectively. Factors related to post-lockdown anxiety were female sex (2.5; 1.01-6.3), Crohn's disease (3.3; 1.3-8.5), and active IBD (4.1; 1.2-13.7). Factors associated with depression were previous history of mood and/or anxiety disorders (6.3; 1.6-24.9), active IBD (7.5; 2.1-26.8), and steroid use (6.4; 1.4-29).
Conclusions: Lockdown during the COVID-19 pandemic had a significant psychological impact in patients with IBD. Disease activity was related to the presence of anxiety and depression symptoms during and after lockdown. (C) 2021 Elsevier Espan tilde a, S.L.U. All rights reserved.
Filiaciones:
Sempere, L:
Hosp Gen Univ Alicante, Inst Invest Sanitaria ISABIAL, Serv Med Digest, Alicante, Spain
Grp Working Crohns Dis & Ulcerat Colitis GETECCU, Madrid, Spain
Bernabeu, P:
Hosp Gen Univ Alicante, Inst Invest Sanitaria ISABIAL, Hlth Psychol Dept, Alicante, Spain
Cameo, J:
Hosp Gen Univ Alicante, Inst Invest Sanitaria ISABIAL, Serv Med Digest, Alicante, Spain
Grp Working Crohns Dis & Ulcerat Colitis GETECCU, Madrid, Spain
Gutierrez, A:
Hosp Gen Univ Alicante, Inst Invest Sanitaria ISABIAL, Serv Med Digest, Alicante, Spain
Grp Working Crohns Dis & Ulcerat Colitis GETECCU, Madrid, Spain
:
Hosp Univ San Juan, Serv Med Digest, Alicante, Spain
Grp Working Crohns Dis & Ulcerat Colitis GETECCU, Madrid, Spain
:
Hosp Gen Univ Elche, Serv Med Digest, Alicante, Spain
Grp Working Crohns Dis & Ulcerat Colitis GETECCU, Madrid, Spain
Aguas, M:
Hosp Univ & Politecn la Fe, Serv Med Digest, Valencia, Spain
CIBERESP Ctr Invest Biomed Red Epidemiol & Salud, Madrid, Spain
Grp Working Crohns Dis & Ulcerat Colitis GETECCU, Madrid, Spain
Zapater, P:
Hosp Gen Univ Alicante, Inst Invest Sanitaria ISABIAL, Clin Pharmachol Dept, Alicante, Spain
Jover, R:
Hosp Gen Univ Alicante, Inst Invest Sanitaria ISABIAL, Serv Med Digest, Alicante, Spain
Ruiz-Cantero, M:
Univ Alicante, Publ Hlth Dept, Alicante, Spain
CIBERESP Ctr Invest Biomed Red Epidemiol & Salud, Madrid, Spain
van-der Hofstadt, C:
Hosp Gen Univ Alicante, Inst Invest Sanitaria ISABIAL, Hlth Psychol Dept, Alicante, Spain
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