Severe Acute Respiratory Syndrome Coronavirus 2 Adaptive Immunity in Nursing Home Residents Following a Third Dose of the Comirnaty Coronavirus Disease 2019 Vaccine
Por:
Giménez E, Albert E, Zulaica J, Torres I, Rusu L, Rodríguez Moreno A, Burgos JS, Peiró S, Salas D, Vanaclocha H, Limón R, Alcaraz MJ, Sánchez-Payá J, Díez-Domingo J, Comas I, Gonzáles-Candelas F, Geller R and Navarro D
Publicada:
24 ago 2022
Ahead of Print:
1 mar 2022
Resumen:
A third Comirnaty vaccine dose increased severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain antibody levels (median, 93-fold) and neutralizing antibody titers against Wuhan-Hu-1 (median, 57-fold), Beta (me 22-fold), Delta, (median, 43-fold), and Omicron (median, 8-fold) variants, but had less impact on S-reactive T-cell immunity in nursing home residents.
Filiaciones:
Giménez E:
Microbiology Service, Clinic University Hospital, INCLIVA Health Research Institute, Valencia, Spain
Albert E:
Microbiology Service, Clinic University Hospital, INCLIVA Health Research Institute, Valencia, Spain
Zulaica J:
Institute for Integrative Systems Biology (I2SysBio), Universitat de Valencia-CSIC, Valencia, Spain
Torres I:
Microbiology Service, Clinic University Hospital, INCLIVA Health Research Institute, Valencia, Spain
Rusu L:
Institute for Integrative Systems Biology (I2SysBio), Universitat de Valencia-CSIC, Valencia, Spain
Rodríguez Moreno A:
Institute for Integrative Systems Biology (I2SysBio), Universitat de Valencia-CSIC, Valencia, Spain
Burgos JS:
General Directorate of Research and Healthcare Supervision, Department of Health, Valencia Government, Valencia, Spain
:
Foundation for the promotion of health and biomedical research of the Valencian Community (FISABIO), Valencia, Spain
:
Foundation for the promotion of health and biomedical research of the Valencian Community (FISABIO), Valencia, Spain
General Directorate of Public Health, Department of Health, Valencia Government, Valencia, Spain
:
General Directorate of Public Health, Department of Health, Valencia Government, Valencia, Spain
Limón R:
General Directorate of Healthcare. Department of Health, Valencian Government, Valencia, Spain
Alcaraz MJ:
Microbiology Service, Clinic University Hospital, INCLIVA Health Research Institute, Valencia, Spain
Sánchez-Payá J:
Preventive Medicine Service, Alicante General and University Hospital, Alicante, Spain
Alicante Institute of Health and Biomedical Research (ISABIAL), Alicante, Spain
:
Foundation for the promotion of health and biomedical research of the Valencian Community (FISABIO), Valencia, Spain
:
Biomedicine Institute of Valencia, Spanish Research Council (CSIC), Valencia, Spain
CIBER in Epidemiology and Public Health, Spain
Joint Research Unit "Infection and Public Health" FISABIO-University of Valencia, Valencia, Spain
:
Institute for Integrative Systems Biology (I2SysBio), Universitat de Valencia-CSIC, Valencia, Spain
CIBER in Epidemiology and Public Health, Spain
Joint Research Unit "Infection and Public Health" FISABIO-University of Valencia, Valencia, Spain
Geller R:
Institute for Integrative Systems Biology (I2SysBio), Universitat de Valencia-CSIC, Valencia, Spain
Navarro D:
Microbiology Service, Clinic University Hospital, INCLIVA Health Research Institute, Valencia, Spain
Department of Microbiology, School of Medicine, University of Valencia, Valencia, Spain
Bronze, Green Published
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