Diagnostic yield of pancreatic percutaneous puncture depending on the size of the lesion
Por:
Fortea-Sanchis C, Gómez-Quiles L, Martínez-Ramos D, Escrig Sos J, Paiva-Coronel GA, Queralt-Martín R, Villarín-Rodríguez Á, Granel-Villach L and Salvador-Sanchis JL
Publicada:
1 jun 2013
Ahead of Print:
13 feb 2013
Categoría:
Surgery
Resumen:
Introduction: The aim of the present study was to study the diagnostic efficacy of the percutaneous puncture of pancreatic tissue.
Material and methods: A retrospective study was conducted on patients with suspicion of pancreatic neoplasm, and with a percutaneous biopsy of pancreatic tissue, from 2000to 2011. For the statistical comparative analysis, the sample was stratified by tumour size: <= 3 cm and > 3 cm.
Results: A total of 90 biopsies were performed. Pancreatic neoplasm diagnosis was made in 47 cases (52%), with 16 false negatives (18%), no false positives, and chronic pancreatitis in 24 cases (27%). The efficacy of the test results were: an overall sensitivity of 75% (95% CI: 62%-85%), a specificity of 100% (95% CI: 87%-100%), a positive predictive value of 100% (95% CI: 92%-100%), and a negative predictive value of 63% (95% CI: 46%-77%). For tumour sizes <= 3 cm the sensitivity was 70% (95% CI: 45%-88%), with a specificity of 100% (95% CI 66%-100%), a positive predictive value of 100% (95% CI: 76%-100%, and a negative predictive value 60% (95% CI: 32%-83%). For tumours greater than 3 cm, the sensitivity was 88% (95% CI: 70%-98%), the specificity was 100% (95% CI: 75%-100%), with a positive predictive value of 100% (95% CI: 85%-100%) and a negative predictive value of 81% (95% CI: 54%-96%).
Conclusions: Pancreatic percutaneous biopsy efficacy was strongly determined by lesion size. For tumour sizes less than 3 cm, the sensitivity and negative predictive value are unacceptably low, as negative results would not reliable. (C) 2012 AEC. Published by Elsevier Espana, S.L. All rights reserved.
Filiaciones:
:
Servicio de Cirugía General y Digestiva, Hospital General, Castellón, España.
Open Access
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