Influence of weight status on bone mineral content measured by DXA in children
Por:
Ferrer FS, Cortes E, Marco FC, Ruiz MJ, Rico JAQ and Roca APN
Publicada:
20 abr 2021
Ahead of Print:
20 abr 2021
Categoría:
Pediatrics, perinatology and child health
Resumen:
Introduction Childhood obesity is a public health problem with repercussions in later life. As tissue formation peaks in childhood we determined how weight status influences bone mineral content. Material and methods We studied 553 children aged 4-18 years over 10 years (46.8% girls). We measured age, weight, height and through bone densitometry (DXA), bone mineral content (BMC), bone mineral density (BMD), and waist, arm and hip circumferences. The patients were divided into groups using the body mass index z-score: underweight, normal weight, overweight, obese and very obese. Results BMC and BMD values were highest in the normal-weight and overweight groups. Logistic regression showed bone mineralization was inversely associated with waist circumference, the association being positive for weight and age. No differences were found according to sex. Discussion Studies of the relationship between weight and bone mineralization report contradictory results, often because of different study designs. Moreover, studies in children are either few or with small samples. Our findings in a large sample show the importance of weight status in bone mineralization given the risk of bone fractures or osteoporosis. Conclusions Weight status influenced bone mineralization. BMC and BMD decreased in children with a higher degree of obesity. Waist circumference correlated negatively with bone mineralization.
Filiaciones:
:
Medical School, University of Miguel Hernández de Elche, Sant Joan d'Alacant, Spain
Hospital Universitario de San Juan de Alicante, Ctra N-332, s/n, 03550, Sant Joan d'Alacant, Alicante, Spain
Cortes E:
Medical School, University of Miguel Hernández de Elche, Sant Joan d'Alacant, Spain.
:
Medical School, University of Miguel Hernández de Elche, Sant Joan d'Alacant, Spain
Hospital Universitario de San Juan de Alicante, Ctra N-332, s/n, 03550, Sant Joan d'Alacant, Alicante, Spain
:
Medical School, University of Miguel Hernández de Elche, Sant Joan d'Alacant, Spain
:
Medical School, University of Miguel Hernández de Elche, Sant Joan d'Alacant, Spain
:
Medical School, University of Miguel Hernández de Elche, Sant Joan d'Alacant, Spain
Hospital Universitario de San Juan de Alicante, Ctra N-332, s/n, 03550, Sant Joan d'Alacant, Alicante, Spain
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