Urban environment and cognitive and motor function in children from four European birth cohorts


Por: Binter AC, Bernard JY, Mon-Williams M, Andiarena A, González-Safont L, Vafeiadi M, Lepeule J, Soler-Blasco R, Alonso L, Kampouri M, Mceachan R, Santa-Marina L, Wright J, Chatzi L, Sunyer J, Philippat C, Nieuwenhuijsen M, Vrijheid M and Guxens M

Publicada: 1 ene 2022 Ahead of Print: 1 oct 2021
Categoría: Environmental science (miscellaneous)

Resumen:
Background: The urban environment may influence neurodevelopment from conception onwards, but there is no evaluation of the impact of multiple groups of exposures simultaneously. We investigated the association between early-life urban environment and cognitive and motor function in children. Methods: We used data from 5403 mother-child pairs from four population-based birth-cohorts (UK, France, Spain, and Greece). We estimated thirteen urban home exposures during pregnancy and childhood, including: built environment, natural spaces, and air pollution. Verbal, non-verbal, gross motor, and fine motor functions were assessed using validated tests at five years old. We ran adjusted multi-exposure models using the Deletion-Substitution-Addition algorithm. Results: Higher greenness exposure within 300 m during pregnancy was associated with higher verbal abilities (1.5 points (95% confidence interval 0.4, 2.7) per 0.20 unit increase in greenness). Higher connectivity density within 100 m and land use diversity during pregnancy were related to lower verbal abilities. Childhood exposure to PM2.5 mediated 74% of the association between greenness during childhood and verbal abilities. Higher exposure to PM2.5 during pregnancy was related to lower fine motor function (-1.2 points (-2.1, -0.4) per 3.2 mu g/m3 increase in PM2.5). No associations were found with non-verbal abilities and gross motor function. Discussion: This study suggests that built environment, greenness, and air pollution may impact child cognitive and motor function at five years old. This study adds evidence that well-designed urban planning may benefit children's cognitive and motor development.

Filiaciones:
Binter AC:
 ISGlobal, Barcelona, Spain

 Universitat Pompeu Fabra (UPF), Barcelona, Spain

 CIBER Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Spain

Bernard JY:
 Université de Paris, Centre for Research in Epidemiology and StatisticS (CRESS), Inserm, INRAE, F-75004 Paris, France

 Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore

Mon-Williams M:
 Bradford Institute for Health Research, Bradford, West Yorkshire, UK

 School of Psychology, University of Leeds, Leeds, UK

 National Centre for Optics, Vision and Eye Care, University of South-Eastern Norway, Kongsberg, Norway

Andiarena A:
 Faculty of Psychology, University of the Basque Country (UPV/EHU), Donostia-San Sebastián, Spain

 Biodonostia, Environmental Epidemiology and Child Development Group, 20014 San Sebastian, Spain

:
 CIBER Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Spain

 Epidemiology and Environmental Health Joint Research Unit, FISABIO -Universitat Jaume I -Universitat de Val ència, Valencia, Spain

Vafeiadi M:
 Department of Social Medicine, Faculty of Medicine, University of Crete, 71003 Heraklion, Crete, Greece

Lepeule J:
 University Grenoble Alpes, Inserm, CNRS, Team of Environmental Epidemiology applied to Reproduction and Respiratory Health, Institute for Advanced Biosciences (IAB), Grenoble, France

:
 Epidemiology and Environmental Health Joint Research Unit, FISABIO -Universitat Jaume I -Universitat de Val ència, Valencia, Spain

Alonso L:
 ISGlobal, Barcelona, Spain

 Universitat Pompeu Fabra (UPF), Barcelona, Spain

 CIBER Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Spain

Kampouri M:
 Department of Social Medicine, Faculty of Medicine, University of Crete, 71003 Heraklion, Crete, Greece

 Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

Mceachan R:
 Bradford Institute of Health Research, Bradford BD9 6RJ, United Kingdom

Santa-Marina L:
 Epidemiology and Environmental Health Joint Research Unit, FISABIO -Universitat Jaume I -Universitat de Val ència, Valencia, Spain

 Biodonostia, Epidemiology and Public Health Area, Environmental Epidemiology and Child Development Group, 20014 San Sebastian, Spain

 Public Health Division of Gipuzkoa, Basque Government, 20013 San Sebastian, Spain

Wright J:
 Bradford Institute of Health Research, Bradford BD9 6RJ, United Kingdom

Chatzi L:
 Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, US

Sunyer J:
 ISGlobal, Barcelona, Spain

 Universitat Pompeu Fabra (UPF), Barcelona, Spain

 CIBER Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Spain

 IMIM-Parc Salut Mar, Barcelona

Philippat C:
 University Grenoble Alpes, Inserm, CNRS, Team of Environmental Epidemiology applied to Reproduction and Respiratory Health, Institute for Advanced Biosciences (IAB), Grenoble, France

Nieuwenhuijsen M:
 ISGlobal, Barcelona, Spain

 Universitat Pompeu Fabra (UPF), Barcelona, Spain

 CIBER Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Spain

Vrijheid M:
 ISGlobal, Barcelona, Spain

 Universitat Pompeu Fabra (UPF), Barcelona, Spain

 CIBER Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Spain

Guxens M:
 ISGlobal, Barcelona, Spain

 Universitat Pompeu Fabra (UPF), Barcelona, Spain

 CIBER Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Spain

 Department of Child and Adolescent Psychiatry, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands
ISSN: 01604120





ENVIRONMENT INTERNATIONAL
Editorial
PERGAMON-ELSEVIER SCIENCE LTD, Netherlands, Reino Unido
Tipo de documento: Article
Volumen: 158 Número:
Páginas: 106933-106933
WOS Id: 000710097200003
ID de PubMed: 34662798
imagen Green Published, gold

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