Characteristics of Patients With Immune-Mediated Inflammatory Diseases Hospitalized for SARS-CoV-2 Infection.
Por:
Robustillo-Villarino M, Álvarez-Arroyo L, Carrera-Hueso FJ, Barreda-Altaba I, Nieto-Cid M, Girona-Sanz AM and El-Qutob D
Ahead of Print:
20 mar 2021
Resumen:
BACKGROUND: Immune-mediated inflammatory diseases (IMID) predispose to a higher infection risk by modifying the host's immune response, which acts as a key factor in SARS-CoV-2 infection resolution. Recent publications show that IMID patients and its treatments do not worsen the outcome of SARS-CoV-2 infection. OBJECTIVES: To describe the clinical characteristics and outcomes of patients with IMID who required hospital admission due to SARS-CoV-2 infection. Secondly, to compare clinical characteristics and outcomes between patients who required hospital admission due to SARS-CoV-2 infection with IMID and those who were not affected. METHODS: We performed an observational retrospective cohort study, including admitted patients with suspected SARS-CoV-2 infection, treated according to medical criteria and local protocols based on the best available scientific evidence. Clinical data were collected from their electronical clinical history. Statistical analysis determined the differences in the characteristics and clinical outcome of the infection in IMID patients. RESULTS: Of a total number of 612 revised patients, 23 had an IMID and 9 of them were positive for the SARS-CoV-2 infection. We did not observe a correlation between these two disorders. There was a higher frequency of obesity and cardiovascular disease among IMID patients, but without statistical significance. The clinical outcomes were no different between hospitalized IMID and non IMID patients. CONCLUSION: IMID and its treatments do not determine the outcome of patients admitted with SARS-CoV-2 infection.
Filiaciones:
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Sección de Reumatología, Servicio de Medicina Interna, Hospital Universitario de la Plana, Villarreal, Castellón, España
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Servicio de Farmacia, Hospital Universitario de la Plana, Villarreal, Castellón, España
Programa de doctorado en Farmacia, Universidad de Granada, Granada, España
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Servicio de Farmacia, Hospital Universitario de la Plana, Villarreal, Castellón, España
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Servicio de Neurofisiología, Hospital Universitario de la Plana, Villarreal, Castellón, España
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Unidad de Alergología, Servicio de Medicina Interna, Hospital Universitario de la Plana, Villarreal, Castellón, España
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Sección de Medicina Digestiva, Servicio de Medicina Interna, Hospital Universitario de la Plana, Villarreal, Castellón, España
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Unidad de Alergología, Servicio de Medicina Interna, Hospital Universitario de la Plana, Villarreal, Castellón, España
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