Education-based approach to addressing non-evidence-based practice in preventing NSAID-associated gastrointestinal complications


Por: Lanas, A, Esplugues, J, Zapardiel, J and Sobreviela, E

Publicada: 21 dic 2009
Resumen:
AIM: To evaluate an evidence-based educational program for improving strategies for prevention of nonsteroidal anti-inflammatory drug (NSAID)-associated gastrointestinal (GI) complications. METHODS: Four hundred and fifty-six specialists replied to a questionnaire that covered issues related to NSAID-induced adverse effects. They also collected data from their last five consecutive patients before and after they had attended an evidence-based seminar on GI prevention strategies. RESULTS: Four hundred and forty-one of 456 specialists (96.7%) participated in the survey, and 382 (83.7%) in the education-based study that recorded data from 3728 patients. The specialists overestimated the risk of GI complications with NSAIDs, underestimated the GI safety profile of coxibs, but were aware of the risk factors and of the current prevention strategies. Proton pump inhibitors were co-prescribed with NSAIDs in > 80% of patients with and without risk factors. The educational program had little impact on prescribing habits. CONCLUSION: Specialists are informed of advances in NSAID-associated adverse effects and have high rates of GI-prevention therapy. Our educational program did not alter these rates. (C) 2009 The WJG Press and Baishideng. All rights reserved.

Filiaciones:
Lanas, A:
 Univ Zaragoza, Serv Digest Dis, Univ Hosp, IACS,CIBERehd, E-50009 Zaragoza, Spain

:
 Univ Valencia, Dept Pharmacol, CIBERehd, E-46100 Valencia, Spain

Zapardiel, J:
 AstraZeneca Farmaceut Spain, Dept Med, Madrid 28033, Spain

Sobreviela, E:
 MediClin Quintiles, Barcelona 08024, Spain
ISSN: 10079327





WORLD JOURNAL OF GASTROENTEROLOGY
Editorial
BAISHIDENG PUBLISHING GROUP INC, 8226 REGENCY DR, PLEASANTON, CA 94588 USA, China
Tipo de documento: Article
Volumen: 15 Número: 47
Páginas: 5953-5959
WOS Id: 000273077400008
ID de PubMed: 20014459
imagen Green Published

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