Frequency, risk factors, and outcomes of hospital readmissions of COVID-19 patients
Por:
Ramos-Martínez A, Parra-Ramírez LM, Morrás I, Carnevali M, Jiménez-Ibañez L, Rubio-Rivas M, Arnalich F, Beato JL, Monge D, Asín U, Suárez C, Freire SJ, Méndez-Bailón M, Perales I, Loureiro-Amigo J, Gómez-Belda AB, Pesqueira PM, Gómez-Huelgas R, Mella C, Díez-García LF, Fernández-Sola J, González-Ferrer R, Aroza M, Antón-Santos JM and Bermejo CL
Publicada:
2 jul 2021
Ahead of Print:
2 jul 2021
Categoría:
Multidisciplinary
Resumen:
To determine the proportion of patients with COVID-19 who were readmitted to the hospital and the most common causes and the factors associated with readmission. Multicenter nationwide cohort study in Spain. Patients included in the study were admitted to 147 hospitals from March 1 to April 30, 2020. Readmission was defined as a new hospital admission during the 30 days after discharge. Emergency department visits after discharge were not considered readmission. During the study period 8392 patients were admitted to hospitals participating in the SEMI-COVID-19 network. 298 patients (4.2%) out of 7137 patients were readmitted after being discharged. 1541 (17.7%) died during the index admission and 35 died during hospital readmission (11.7%, p=0.007). The median time from discharge to readmission was 7 days (IQR 3-15 days). The most frequent causes of hospital readmission were worsening of previous pneumonia (54%), bacterial infection (13%), venous thromboembolism (5%), and heart failure (5%). Age [odds ratio (OR): 1.02; 95% confident interval (95% CI): 1.01-1.03], age-adjusted Charlson comorbidity index score (OR: 1.13; 95% CI: 1.06-1.21), chronic obstructive pulmonary disease (OR: 1.84; 95% CI: 1.26-2.69), asthma (OR: 1.52; 95% CI: 1.04-2.22), hemoglobin level at admission (OR: 0.92; 95% CI: 0.86-0.99), ground-glass opacification at admission (OR: 0.86; 95% CI:0.76-0.98) and glucocorticoid treatment (OR: 1.29; 95% CI: 1.00-1.66) were independently associated with hospital readmission. The rate of readmission after hospital discharge for COVID-19 was low. Advanced age and comorbidity were associated with increased risk of readmission.
Filiaciones:
Ramos-Martínez A:
Infectious Diseases Unit, Internal Medicine Department, Hospital Universitario Puerta de Hierro-Majadahonda UAM, IDIPHSA, Maestro Rodrigo 2, 28222, Majadahonda, Madrid, Spain.
Infectious Diseases Unit, Hospital Universitario Puerte de Hierro-Majadahonda Majadahonda, Calle Maestro Rodrigo 2, 28222, Majadahonda, Madrid, Spain.
Parra-Ramírez LM:
Preventive Medicine Department, Hospital Universitario Puerta de Hierro-Majadahonda UAM, IDIPHSA, Maestro Rodrigo 2, 28222, Majadahonda, Madrid, Spain
Morrás I:
Internal Medicine Department, Hospital Universitario Puerta de Hierro-Majadahonda UAM, IDIPHSA, Maestro Rodrigo 2, 28222, Majadahonda, Madrid, Spain
Carnevali M:
Internal Medicine Department, 12 de Octubre University Hospital, Av. de Córdoba, s/n, 28041, Madrid, Spain
Jiménez-Ibañez L:
Internal Medicine Department, Gregorio Marañon University Hospital, Dr. Esquerdo, 46, 28007, Madrid, Spain
Rubio-Rivas M:
Internal Medicine Department, Bellvitge University Hospital, Carrer de La Feixa Llarga, s/n, 08907, L'Hospitalet de Llobregat, Barcelona, Spain
Arnalich F:
Internal Medicine Department, La Paz University Hospital, Paseo de La Castellana, 261, 28046, Madrid, Spain
Beato JL:
Internal Medicine Department, Albacete University Hospital Complex, Hermanos Falco, 37, 02006, Albacete, Spain
Monge D:
Internal Medicine Department, Segovia Hospital Complex, Luis Erik Clavería Neurólogo s/n, 40002, Segovia, Spain
Asín U:
Internal Medicine Department, Miguel Servet Hospital, Paseo Isabel la Católica, 1-3, 50009, Zaragoza, Spain
Suárez C:
Internal Medicine Department, La Princesa University Hospital, Diego de León, 62, 28006, Madrid, Spain
Freire SJ:
Internal Medicine Department, A Coruña University Hospital, Xubias de Arriba, 84, 15006 A, Coruña, Spain
Méndez-Bailón M:
Internal Medicine Department, San Carlos Clinical Hospital, Prof Martín Lagos, s/n, 28040, Madrid, Spain
Perales I:
Internal Medicine Department, Infanta Sofía Hospital, Paseo de Europa, 34, 28703, San Sebastián de los Reyes, Madrid, Spain
Loureiro-Amigo J:
Internal Medicine Department, Moisès Broggi Hospital, Carrer de Jacint Verdaguer, 90, 08970, Sant Joan Despí, Barcelona, Spain
:
Internal Medicine Department, Dr. Peset University Hospital, Av. de Gaspar Aguilar, 90, 46017, Valencia, Spain
Pesqueira PM:
Internal Medicine Department, Santiago Clinical Hospital, Rúa da Choupana, s/n, 15706, Santiago de Compostela, A Coruña, Spain
Gómez-Huelgas R:
Internal Medicine Department, Regional University Hospital of Málaga, Biomedical Research Institute of Málaga (IBIMA), University of Málaga (UMA), Av. de Carlos Haya, 84, 29010, Málaga, Spain
Mella C:
Internal Medicine Department, Hospital Architect Marcide-Novoa Santos, Rúa Pardo Bazán, s/n, 15404, Ferrol, A Coruña, Spain
Díez-García LF:
Internal Medicine Department, Torrecárdenas Hospital, Hermandad de Donantes de Sangre, s/n, 04009, Almería, Spain
Fernández-Sola J:
Internal Medicine Department, Clinic Barcelona Hospital, Villarroel, 170, 08036, Barcelona, Spain
González-Ferrer R:
Internal Medicine Department, Tajo Hospital, Av. Amazonas Central, s/n, 28300, Aranjuez, Madrid, Spain
Aroza M:
Internal Medicine Department, Insular de Gran Canaria Hospital, Av. Marítima del Sur, s/n, 35016, Las Palmas de Gran Canaria, Las Palmas, Spain
Antón-Santos JM:
Internal Medicine Department, Infanta Cristina University Hospital, Av. 9 de Junio, 2, 28981, Parla, Madrid, Spain
Bermejo CL:
Internal Medicine Department, 12 de Octubre University Hospital, Av. de Córdoba, s/n, 28041, Madrid, Spain
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