Prognostic accuracy of Quick SOFA in older adults hospitalised with community acquired urinary tract infection
Por:
Madrazo M, López-Cruz I, Zaragoza R, Piles L, Eiros JM, Alberola J and Artero A
Publicada:
21 jul 2021
Ahead of Print:
1 jul 2021
Categoría:
Medicine (miscellaneous)
Resumen:
Introduction Quick [Sepsis-related] Sequential Organ Failure Assessment (qSOFA) is a prognostic score based on sepsis-3 definition, easy to carry out, whose application has been studied in older adults with sepsis from different sources and respiratory sepsis. However, to date no study has analysed its prognostic accuracy in older adults admitted to hospital with community urinary tract infection. Methods In a prospective study of 282 older adults admitted to hospital with community acquired urinary tract infection, the application of qSOFA to predict hospital mortality was analysed. The predictive capacity of qSOFA for in-hospital mortality was compared with Systemic Inflammatory Response Syndrome score (SIRS) and Sequential Organ Failure Assessment (SOFA), which require laboratory test in order to be calculated. Results In a population with a median age of 81 years, where 51.8% were males and 10.6% had septic shock, qSOFA showed sensibility and specificity of 88.46 and 75.78% and area under the receiver operating characteristic curves (AUROC) of 0.810. AUROC for qSOFA was significantly higher than that of SIRS (AUROC 0.597, P = .005) and with no statistical differences with SOFA (AUROC 0.841, P = .635). Conclusion qSOFA showed a better predictive prognostic accuracy than SIRS and similar to SOFA in older adults admitted to hospital with community acquired urinary tract infection, having the advantage of not requiring laboratory tests.
Filiaciones:
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Department of Internal Medicine, Doctor Peset University Hospital. Av, Gaspar Aguilar n 90, Postal code 46017, Valencia, Spain
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Department of Internal Medicine, Doctor Peset University Hospital. Av, Gaspar Aguilar n 90, Postal code 46017, Valencia, Spain
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Intensive Medicine Unit, Doctor Peset University Hospital. Av, Gaspar Aguilar n 90, Postal code 46017, Valencia, Spain
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Department of Internal Medicine, Doctor Peset University Hospital. Av, Gaspar Aguilar n 90, Postal code 46017, Valencia, Spain
Eiros JM:
Department of Microbiology and Parasitology, Rio Hortega University Hospital, University of Valladolid, C/ Dulzaina, Postal code, 47012, Valladolid, Spain
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Department of Microbiology. Doctor, Peset University Hospital, University of Valencia. Av, Gaspar Aguilar n 90, Postal code 46017, Valencia, Spain
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Department of Internal Medicine. Doctor, Peset University Hospital, University of Valencia. Av, Gaspar Aguilar n 90, Postal code 46017, Valencia, Spain
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